|
|
eF-site ID
|
5x21-A |
|
PDB Code
|
5x21 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) |
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Classification
|
TRANSFERASE/DNA |
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Compound
|
DNA-directed RNA polymerase subunit alpha |
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Source
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ORGANISM_SCIENTIFIC: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); |
|
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Sequence
|
A: |
SKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRI
LLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLK
ELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVEIM
NPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRIN
AIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDG
SVTPLEALNQAVEILREHLTYFSNPQ
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|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
51 |
| type |
|
| sequence |
T
|
| description |
binding site for residue MG A 2001
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
170 |
| type |
|
| sequence |
V
|
| description |
binding site for residue MG A 2001
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
171 |
| type |
|
| sequence |
F
|
| description |
binding site for residue MG A 2001
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
172 |
| type |
|
| sequence |
S
|
| description |
binding site for residue MG A 2001
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
175 |
| type |
|
| sequence |
R
|
| description |
binding site for residue MG A 2001
|
| source |
: AC1
|
|
|
|