eF-site ID 5x07-F
PDB Code 5x07
Chain F

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Title Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
Classification DNA BINDING PROTEIN/DNA
Compound DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3')
Source Homo sapiens (Human) (FOXA2_HUMAN)
Sequence F:  GPHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFP
FYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT
LHPDS
Description (1)  Hepatocyte nuclear factor 3-beta/DNA Complex


Functional site

1) chain F
residue 212
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P32182
source Swiss-Prot : SWS_FT_FI2

2) chain F
residue 159-172
type prosite
sequence KPPYSYISLITMAI
description FORK_HEAD_1 Fork head domain signature 1. KPPYSYisLitm.AI
source prosite : PS00657

3) chain F
residue 203-209
type prosite
sequence WQNSIRH
description FORK_HEAD_2 Fork head domain signature 2. WQNSIRH
source prosite : PS00658


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