|
eF-site ID
|
5x07-F |
PDB Code
|
5x07 |
Chain
|
F |
|
click to enlarge
|
|
Title
|
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site |
Classification
|
DNA BINDING PROTEIN/DNA |
Compound
|
DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3') |
Source
|
Homo sapiens (Human) (FOXA2_HUMAN) |
|
Sequence
|
F: |
GPHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFP
FYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT
LHPDS
|
|
Description
|
(1) |
Hepatocyte nuclear factor 3-beta/DNA Complex
|
|
Functional site
|
|
1)
|
chain |
F |
residue |
212 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine => ECO:0000250|UniProtKB:P32182
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
2)
|
chain |
F |
residue |
159-172 |
type |
prosite |
sequence |
KPPYSYISLITMAI
|
description |
FORK_HEAD_1 Fork head domain signature 1. KPPYSYisLitm.AI
|
source |
prosite : PS00657
|
|
3)
|
chain |
F |
residue |
203-209 |
type |
prosite |
sequence |
WQNSIRH
|
description |
FORK_HEAD_2 Fork head domain signature 2. WQNSIRH
|
source |
prosite : PS00658
|
|
|
|