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eF-site ID
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5wxd-A |
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PDB Code
|
5wxd |
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Chain
|
A |
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click to enlarge
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Title
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Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) |
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Classification
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IMMUNE SYSTEM |
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Compound
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HLA class I histocompatibility antigen, A-24 alpha chain |
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Source
|
(5WXD) |
|
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Sequence
|
A: |
GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA
ASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRI
ALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDG
KDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYL
EGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT
FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW
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Description
|
(1) |
HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, H7-25
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
257-263 |
| type |
prosite |
| sequence |
YTCHVQH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
|
| source |
prosite : PS00290
|
|
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2)
|
chain |
A |
| residue |
73 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
A |
| residue |
84 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
143 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
146 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
171 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
159 |
| type |
CARBOHYD |
| sequence |
Y
|
| description |
N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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8)
|
chain |
A |
| residue |
86 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI4
|
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