eF-site ID 5wwp-B PDB Code 5wwp Chain B click to enlarge Title Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13) Classification HYDROLASE Compound ORF1ab Source Human betacoronavirus 2c EMC/2012 (K0BWD0_9BETC) Sequence B:  PAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPH KMVLSVSPYVCNAPGCGVSDVTKLYLGGMSYFCVDHRPVC SFPLCANGLVFGLYKNMCTGSPSIVEFNRLATCDWTESGD YTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVG ERQLLLVWEAGKSKPPLNRNYVFTGYKVQLGEYIFERIDY SDAVSYKSSTTYKLTVGDIFVLTSHSVATLTAPTIVNQER YVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGPPG TGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYL NIAKCSRIIPAKARVECYDRFKVNETNSQYLFSTINALPE TSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPAQL PAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSMCYRCP KEIVSTVSALVYNNKLLAKKELSGQCFKILYKGNVTHDAS SAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAVSRSM LGLTTQTVDSSQGSEYQYVIFCQTADTAHANNINRFNVAI TRAQKGILCVMTSQALFESLEFTELSFTNYK Description Functional site 1) chain B residue 5 type sequence C description binding site for residue ZN B 601 source : AC1 2) chain B residue 8 type sequence C description binding site for residue ZN B 601 source : AC1 3) chain B residue 26 type sequence C description binding site for residue ZN B 601 source : AC1 4) chain B residue 29 type sequence C description binding site for residue ZN B 601 source : AC1 5) chain B residue 16 type sequence C description binding site for residue ZN B 602 source : AC2 6) chain B residue 19 type sequence C description binding site for residue ZN B 602 source : AC2 7) chain B residue 33 type sequence H description binding site for residue ZN B 602 source : AC2 8) chain B residue 39 type sequence H description binding site for residue ZN B 602 source : AC2 9) chain B residue 50 type sequence C description binding site for residue ZN B 603 source : AC3 10) chain B residue 55 type sequence C description binding site for residue ZN B 603 source : AC3 11) chain B residue 72 type sequence C description binding site for residue ZN B 603 source : AC3 12) chain B residue 75 type sequence H description binding site for residue ZN B 603 source : AC3 13) chain B residue 284 type sequence P description binding site for residue SO4 B 604 source : AC4 14) chain B residue 285 type sequence G description binding site for residue SO4 B 604 source : AC4 15) chain B residue 288 type sequence K description binding site for residue SO4 B 604 source : AC4 16) chain B residue 443 type sequence R description binding site for residue SO4 B 604 source : AC4

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