eF-site ID 5wwp-A PDB Code 5wwp Chain A click to enlarge Title Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13) Classification HYDROLASE Compound ORF1ab Source Human betacoronavirus 2c EMC/2012 (K0BWD0_9BETC) Sequence A:  PAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPH KMVLSVSPYVCNAPGCGVSDVTKLYLGGMSYFCVDHRPVC SFPLCANGLVFGLYKNMCTGSPSIVEFNRLATCDWTESGD YTLANTTTEPLKLFAAETLRATEEASKSVATLTAPTIVNQ ERYVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGP PGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFK YLNIAKCSRIIPAKARVECYDRFKVNETNSQYLFSTINAL PETSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPA QLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSMCYR CPKEIVSTVSALVYNNKLLAKKELSGQCFKILYKGNVTHD ASSAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAVSR SMLGLTTQTVDSSQGSEYQYVIFCQTADTAHANNINRFNV AITRAQKGILCVMTSQALFESLEFTELSFTNYKLQ Description Functional site 1) chain A residue 5 type sequence C description binding site for residue ZN A 601 source : AC5 2) chain A residue 8 type sequence C description binding site for residue ZN A 601 source : AC5 3) chain A residue 26 type sequence C description binding site for residue ZN A 601 source : AC5 4) chain A residue 29 type sequence C description binding site for residue ZN A 601 source : AC5 5) chain A residue 16 type sequence C description binding site for residue ZN A 602 source : AC6 6) chain A residue 19 type sequence C description binding site for residue ZN A 602 source : AC6 7) chain A residue 33 type sequence H description binding site for residue ZN A 602 source : AC6 8) chain A residue 50 type sequence C description binding site for residue ZN A 603 source : AC7 9) chain A residue 55 type sequence C description binding site for residue ZN A 603 source : AC7 10) chain A residue 72 type sequence C description binding site for residue ZN A 603 source : AC7 11) chain A residue 75 type sequence H description binding site for residue ZN A 603 source : AC7 12) chain A residue 380 type sequence T description binding site for residue SO4 A 604 source : AC8 13) chain A residue 381 type sequence N description binding site for residue SO4 A 604 source : AC8 14) chain A residue 409 type sequence R description binding site for residue SO4 A 604 source : AC8 15) chain A residue 422 type sequence F description binding site for residue SO4 A 604 source : AC8 16) chain A residue 486 type sequence S description binding site for residue SO4 A 605 source : AC9 17) chain A residue 515 type sequence Y description binding site for residue SO4 A 605 source : AC9 18) chain A residue 516 type sequence N description binding site for residue SO4 A 605 source : AC9 19) chain A residue 285 type sequence G description binding site for residue SO4 A 606 source : AD1 20) chain A residue 286 type sequence T description binding site for residue SO4 A 606 source : AD1 21) chain A residue 287 type sequence G description binding site for residue SO4 A 606 source : AD1 22) chain A residue 288 type sequence K description binding site for residue SO4 A 606 source : AD1 23) chain A residue 284 type sequence P description binding site for residue SO4 A 607 source : AD2 24) chain A residue 285 type sequence G description binding site for residue SO4 A 607 source : AD2 25) chain A residue 404 type sequence Q description binding site for residue SO4 A 607 source : AD2 26) chain A residue 443 type sequence R description binding site for residue SO4 A 607 source : AD2 27) chain A residue 538 type sequence G description binding site for residue SO4 A 607 source : AD2 28) chain A residue 567 type sequence R description binding site for residue SO4 A 607 source : AD2

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