|
|
eF-site ID
|
5wob-a |
|
PDB Code
|
5wob |
|
Chain
|
a |
|
click to enlarge
|
|
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Title
|
Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin |
|
Classification
|
HYDROLASE |
|
Compound
|
Insulin-degrading enzyme |
|
Source
|
(5WOB) |
|
|
Sequence
|
a: |
GIVEQCCTSICSLYQLENYC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
a |
| residue |
12 |
| type |
|
| sequence |
S
|
| description |
binding site for residue ZN A 1101
|
| source |
: AC1
|
|
|
2)
|
chain |
a |
| residue |
14 |
| type |
|
| sequence |
Y
|
| description |
binding site for residue ZN A 1101
|
| source |
: AC1
|
|
|
3)
|
chain |
a |
| residue |
6-20 |
| type |
prosite |
| sequence |
CCTSICSLYQLENYC
|
| description |
INSULIN Insulin family signature. CCTSiCSlyqLenyC
|
| source |
prosite : PS00262
|
|
|
|