eF-site ID 5wji-AB PDB Code 5wji Chain A, B click to enlarge Title Crystal structure of the F61S mutant of HsNUDT16 Classification HYDROLASE Compound U8 snoRNA-decapping enzyme Source (NUD16_HUMAN) Sequence A:  ARRLELGEALALGSGWRHVCHALLYAPDPGMLFGRIPLRY AILMQMRFDGRLGFPGGSVDTQDRSLEDGLNRELREELGE AAAAFRVERTDYRSSHVGPRVVAHFYAKRLTLEELLAVEA GATRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSFIG SAREQLLEALQDLGLL B:  RRLELGEALALGSGWRHVCHALLYAPDPGMLFGRIPLRYA ILMQMRFDGRLGFPGGSVDTQDRSLEDGLNRELREELGEA AAAFRVERTDYRSSHVPRVVAHFYAKRLTLEELLAVEAGA TRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSFIGSA REQLLEALQDLGLL Description Functional site 1) chain A residue 28 type sequence Y description binding site for residue SO4 A 302 source : AC1 2) chain A residue 96 type sequence R description binding site for residue SO4 A 302 source : AC1 3) chain A residue 174 type sequence A description binding site for residue SO4 A 302 source : AC1 4) chain A residue 177 type sequence D description binding site for residue SO4 A 302 source : AC1 5) chain A residue 178 type sequence L description binding site for residue SO4 A 302 source : AC1 6) chain A residue 63 type sequence D description binding site for residue ACY A 303 source : AC2 7) chain A residue 64 type sequence T description binding site for residue ACY A 303 source : AC2 8) chain A residue 66 type sequence D description binding site for residue ACY A 303 source : AC2 9) chain A residue 57 type BINDING sequence F description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 170 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 24 type BINDING sequence H description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 50 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 57 type BINDING sequence F description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 170 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 24 type BINDING sequence H description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 16) chain A residue 50 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 59 type BINDING sequence G description BINDING => ECO:0000269|PubMed:32432673, ECO:0000305|PubMed:26121039, ECO:0007744|PDB:6X7U source Swiss-Prot : SWS_FT_FI2 18) chain B residue 59 type BINDING sequence G description BINDING => ECO:0000269|PubMed:32432673, ECO:0000305|PubMed:26121039, ECO:0007744|PDB:6X7U source Swiss-Prot : SWS_FT_FI2 19) chain A residue 76 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 20) chain A residue 80 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 21) chain B residue 76 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 22) chain B residue 80 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 23) chain A residue 99 type BINDING sequence H description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 24) chain A residue 173 type BINDING sequence E description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 25) chain B residue 99 type BINDING sequence H description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 26) chain B residue 173 type BINDING sequence E description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4

Display surface Download Links