eF-site ID 5wfq-N PDB Code 5wfq Chain N click to enlarge Title Ligand-bound Ras:SOS:Ras complex Classification SIGNALING PROTEIN Compound GTPase HRas Source Homo sapiens (Human) (SOS1_HUMAN) Sequence N:  QMRLPSADVYRFAEPDSEENIIFEENMQGIPIIKAGTVIK LIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERF EIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLR VLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKK WVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFD LLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKE INSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRI IEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPS RQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLT NILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLE IEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR Description Functional site 1) chain N residue 852 type sequence V description binding site for residue 5UV N 1101 source : AC3 2) chain N residue 878 type sequence M description binding site for residue 5UV N 1101 source : AC3 3) chain N residue 879 type sequence N description binding site for residue 5UV N 1101 source : AC3 4) chain N residue 883 type sequence V description binding site for residue 5UV N 1101 source : AC3 5) chain N residue 884 type sequence Y description binding site for residue 5UV N 1101 source : AC3 6) chain N residue 886 type sequence L description binding site for residue 5UV N 1101 source : AC3 7) chain N residue 887 type sequence D description binding site for residue 5UV N 1101 source : AC3 8) chain N residue 890 type sequence F description binding site for residue 5UV N 1101 source : AC3 9) chain N residue 902 type sequence E description binding site for residue 5UV N 1101 source : AC3 10) chain N residue 927-960 type prosite sequence VPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK description RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK source prosite : PS00720

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