eF-site ID 5wfp-R
PDB Code 5wfp
Chain R

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Title Ligand-bound Ras:SOS:Ras complex
Classification SIGNALING PROTEIN
Compound GTPase HRas
Source null (SOS1_HUMAN)
Sequence R:  GMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDS
YRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFL
CVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCD
LAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTL
VREIRQH
Description


Functional site

1) chain R
residue 13
type BINDING
sequence G
description BINDING => ECO:0000269|PubMed:16698776
source Swiss-Prot : SWS_FT_FI1

2) chain R
residue 29
type BINDING
sequence V
description BINDING => ECO:0000269|PubMed:16698776
source Swiss-Prot : SWS_FT_FI1

3) chain R
residue 59
type BINDING
sequence A
description BINDING => ECO:0000269|PubMed:16698776
source Swiss-Prot : SWS_FT_FI1

4) chain R
residue 116
type BINDING
sequence N
description BINDING => ECO:0000269|PubMed:16698776
source Swiss-Prot : SWS_FT_FI1

5) chain R
residue 145
type BINDING
sequence S
description BINDING => ECO:0000269|PubMed:16698776
source Swiss-Prot : SWS_FT_FI1

6) chain R
residue 1
type MOD_RES
sequence M
description N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12
source Swiss-Prot : SWS_FT_FI2

7) chain R
residue 2
type MOD_RES
sequence T
description N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12
source Swiss-Prot : SWS_FT_FI3

8) chain R
residue 118
type MOD_RES
sequence C
description S-nitrosocysteine => ECO:0000269|PubMed:9020151
source Swiss-Prot : SWS_FT_FI4

9) chain R
residue 35
type CARBOHYD
sequence T
description (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486, ECO:0000269|PubMed:8626575, ECO:0000269|PubMed:8626586, ECO:0000269|PubMed:9632667
source Swiss-Prot : SWS_FT_FI5


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