|
Title
|
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle) |
|
Classification
|
VIRUS LIKE PARTICLE/IMMUNE SYSTEM |
|
Compound
|
C5 antibody variable heavy domain |
|
Source
|
ORGANISM_COMMON: Mouse; ORGANISM_SCIENTIFIC: Mus musculus; |
|
|
Sequence
|
A: |
NGSETDVECFLGRAACVHVTEIQNKDATGIDNHREAKLFN
DWKINLSSLVQLRKKLELFTYVRFDSEYTILATASQPDSA
NYSSNLVVQAMYVPPGAPNPKEWDDYTWQSASNPSVFFKV
GDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGITVLNH
MGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRA
LPYTSIGRTNYPKNTEPVIKKRKGDIKSY
|
| B: |
PTTTLPGSGQFLTTDDRQSPSALPNYEPTPRIHIPGKVHN
LLEIIQVDTLIPMNNTHTKDEVNSYLIPLNANRQNEQVFG
TNLFIGDGVFKTTLLGEIVQYYTHWSGSLRFSLMYTGPAL
SSAKLILAYTPPGARGPQDRREAMLGTHVVWDIGLQSTIV
MTIPWTSGVTSAGFLSCWYQTSLILPPETTGQVYLLSFIS
ACPDFKLRLMKDTQT
|
| C: |
VQQITLGNSTITTQEAANAVVCYAEWPEYLDTSVCRFYTL
DSKTWTTGSKGWCWKLPDALKDMGVFGQNMFFHSLGRSGY
TVHVQCNATKFHSGCLLVVVIPEHQLASHEGGNVSVKYTF
THPGERGIDLSSANEVGGPVKDVIYNMNGTLLGNLLIFPH
QFINLRTNNTATIVIPYINSVPIDSMTRHNNVSLMVIPIA
PLTVPTGATPSLPITVTIAPMCTEFSGIRSKSIV
|
| D: |
AVQLAESGPALVAPSQALSITCTVAGFSLTAYGVAWVRQP
PGAGLEWLGAIWAAGATDYNAALKSRASIAKDNSKSQVFL
AMASLATADTAAYYCAREWDAYGDYWGQGTTVTVSA
|
| E: |
DIVLTQSPAALSAAAGATVAATCRASGNIHNALAWYQQKA
GKSPQLLVYAAAALAAGVPSRFSGSGSGTAYALAINSLAA
DDFGAYYCQHFWSTPYTFGGGTKLEIK
|
|
|
Description
|
(1) |
C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, viral protein 3, viral protein 2
|
