eF-site ID 5w2j-ABF PDB Code 5w2j Chain A, B, F click to enlarge Title Crystal structure of dimeric form of mouse Glutaminase C Classification HYDROLASE Compound Glutaminase kidney isoform, mitochondrial Source (5W2J) Sequence A:  SLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKE CMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRR KFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFS PDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAV NDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAG AIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNAT FQSERESGKRNFAIGYYLKEKKCFPEGTDMVGILDFYFQL CSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTL SLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMG MMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFA KKLDPRRE B:  LPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRL KECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAF RRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAK FSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAI AVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVN AGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSN ATFQSERESGKRNFAIGYYLKEKKCFPEGTDMVGILDFYF QLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRN TLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNV MGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRH FAKKLDPRREG F:  AKGALQELGAGLTA Description Functional site 1) chain A residue 290 type sequence Q description binding site for residue CL A 601 source : AC1 2) chain A residue 291 type sequence S description binding site for residue CL A 601 source : AC1 3) chain A residue 471 type sequence Y description binding site for residue CL A 601 source : AC1 4) chain A residue 488 type sequence G description binding site for residue CL A 601 source : AC1 5) chain A residue 489 type sequence V description binding site for residue CL A 601 source : AC1 6) chain B residue 290 type sequence Q description binding site for residue CL B 601 source : AC2 7) chain B residue 291 type sequence S description binding site for residue CL B 601 source : AC2 8) chain B residue 471 type sequence Y description binding site for residue CL B 601 source : AC2 9) chain B residue 488 type sequence G description binding site for residue CL B 601 source : AC2 10) chain B residue 489 type sequence V description binding site for residue CL B 601 source : AC2 11) chain A residue 291 type BINDING sequence S description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 386 type BINDING sequence E description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 393 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 419 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 471 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 489 type BINDING sequence V description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 340 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 386 type BINDING sequence E description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 19) chain A residue 393 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 20) chain A residue 419 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 471 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 489 type BINDING sequence V description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 291 type BINDING sequence S description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 340 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 169 type MOD_RES sequence K description N6-succinyllysine => ECO:0007744|PubMed:23806337 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 169 type MOD_RES sequence K description N6-succinyllysine => ECO:0007744|PubMed:23806337 source Swiss-Prot : SWS_FT_FI2 27) chain A residue 316 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O94925 source Swiss-Prot : SWS_FT_FI3 28) chain B residue 316 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O94925 source Swiss-Prot : SWS_FT_FI3

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