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eF-site ID
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5w0p-A |
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PDB Code
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5w0p |
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Chain
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A |
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click to enlarge
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Title
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Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser |
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Classification
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SIGNALING PROTEIN |
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Compound
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Endolysin,Rhodopsin,S-arrestin |
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Source
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(ARRS_MOUSE) |
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Sequence
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A: |
NIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNA
AKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRN
AKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRML
QQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAY
MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSML
AAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLA
VADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG
GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT
WVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNN
ESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES
ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQG
SCFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTT
ICCGDDEASAXVXKTETSVIFKKVSRDKSVTIYLGKRDYV
DHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDI
DVMGLTFRRDLYFSRVQVYPPVGAMSVLTQLQESLLKKLG
DNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAF
ASDITDPEEDKIPKKSSVRLLIRKVQHAPPEMGPQPSAEA
SWQFFMSDKPLNLSVSLSKEIYFHGEPIPVTVTVTNNTDK
VVKKIKVSVEQIANVVLYSSDYYVKPVASEETQEKVQPNS
TLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTII
KEGIDRTVMGILVSYHIKVKLTVSGFLGELTSSEVATEVP
FRLMHPQPE
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Description
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Functional site
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1)
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chain |
A |
| residue |
123-139 |
| type |
prosite |
| sequence |
IALWSLVVLAIERYVVV
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| description |
G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. IALwSLVVLAIERYVvV
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| source |
prosite : PS00237
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2)
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chain |
A |
| residue |
290-306 |
| type |
prosite |
| sequence |
IPAFFAKSAAIYNPVIY
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| description |
OPSIN Visual pigments (opsins) retinal binding site. IPaFfAKSAAiyNPviY
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| source |
prosite : PS00238
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3)
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chain |
A |
| residue |
2066-2084 |
| type |
prosite |
| sequence |
FRYGQEDIDVMGLTFRRDL
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| description |
ARRESTINS Arrestins signature. FRYGqEDiDVMGLtFrRDL
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| source |
prosite : PS00295
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