eF-site ID 5w0i-A PDB Code 5w0i Chain A click to enlarge Title CREBBP Bromodomain in complex with Cpd8 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) Classification TRANSFERASE/INHIBITOR Compound CREB-binding protein Source Mus musculus (Mouse) (CBP_MOUSE) Sequence A:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG Description Functional site 1) chain A residue 1106 type sequence P description binding site for residue 9UA A 1201 source : AC1 2) chain A residue 1109 type sequence L description binding site for residue 9UA A 1201 source : AC1 3) chain A residue 1110 type sequence P description binding site for residue 9UA A 1201 source : AC1 4) chain A residue 1115 type sequence V description binding site for residue 9UA A 1201 source : AC1 5) chain A residue 1120 type sequence L description binding site for residue 9UA A 1201 source : AC1 6) chain A residue 1122 type sequence I description binding site for residue 9UA A 1201 source : AC1 7) chain A residue 1168 type sequence N description binding site for residue 9UA A 1201 source : AC1 8) chain A residue 1173 type sequence R description binding site for residue 9UA A 1201 source : AC1 9) chain A residue 1174 type sequence V description binding site for residue 9UA A 1201 source : AC1 10) chain A residue 1177 type sequence F description binding site for residue 9UA A 1201 source : AC1 11) chain A residue 1179 type sequence S description binding site for residue 9UA A 1201 source : AC1 12) chain A residue 1186 type sequence E description binding site for residue 9UA A 1201 source : AC1 13) chain A residue 1102 type sequence Y description binding site for residue DMS A 1202 source : AC2 14) chain A residue 1112 type sequence R description binding site for residue DMS A 1202 source : AC2 15) chain A residue 1113 type sequence Q description binding site for residue DMS A 1202 source : AC2 16) chain A residue 1169 type sequence R description binding site for residue DMS A 1203 source : AC3 17) chain A residue 1170 type sequence K description binding site for residue DMS A 1203 source : AC3 18) chain A residue 1109 type sequence L description binding site for residue GOL A 1204 source : AC4 19) chain A residue 1112 type sequence R description binding site for residue GOL A 1204 source : AC4 20) chain A residue 1151 type sequence W description binding site for residue GOL A 1204 source : AC4 21) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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