eF-site ID 5vy2-AB PDB Code 5vy2 Chain A, B click to enlarge Title Crystal structure of the F36A mutant of HsNUDT16 Classification HYDROLASE Compound U8 snoRNA-decapping enzyme Source (NUD16_HUMAN) Sequence A:  ARRLELGEALALGSGWRHVCHALLYAPDPGMLAGRIPLRY AILMQMRFDGRLGFPGGFVDTQDRSLEDGLNRELREELGE AAAAFRVERTDYRSSHVGSGPRVVAHFYAKRLTLEELLAV EAGATRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSF IGSAREQLLEALQDLGLLQ B:  ARRLELGEALALGSGWRHVCHALLYAPDPGMLAGRIPLRY AILMQMRFDGRLGFPGGFVDTQDRSLEDGLNRELREELGE AAAAFRVERTDYRSSHVGSGPRVVAHFYAKRLTLEELLAV EAGATRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSF IGSAREQLLEALQDLGLL Description Functional site 1) chain A residue 76 type sequence E description binding site for residue NA A 201 source : AC1 2) chain A residue 79 type sequence E description binding site for residue NA A 201 source : AC1 3) chain A residue 132 type sequence D description binding site for residue NA A 201 source : AC1 4) chain A residue 136 type sequence E description binding site for residue NA A 201 source : AC1 5) chain A residue 99 type BINDING sequence H description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 6) chain A residue 173 type BINDING sequence E description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 7) chain B residue 99 type BINDING sequence H description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 8) chain B residue 173 type BINDING sequence E description BINDING => ECO:0000269|PubMed:32432673, ECO:0007744|PDB:6X7U, ECO:0007744|PDB:6X7V source Swiss-Prot : SWS_FT_FI4 9) chain A residue 24 type BINDING sequence H description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 50 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 57 type BINDING sequence F description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 170 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 24 type BINDING sequence H description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 50 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 57 type BINDING sequence F description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 170 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:26121039 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 59 type BINDING sequence G description BINDING => ECO:0000269|PubMed:32432673, ECO:0000305|PubMed:26121039, ECO:0007744|PDB:6X7U source Swiss-Prot : SWS_FT_FI2 18) chain B residue 59 type BINDING sequence G description BINDING => ECO:0000269|PubMed:32432673, ECO:0000305|PubMed:26121039, ECO:0007744|PDB:6X7U source Swiss-Prot : SWS_FT_FI2 19) chain A residue 76 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 20) chain A residue 80 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 21) chain B residue 76 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3 22) chain B residue 80 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q6TEC1 source Swiss-Prot : SWS_FT_FI3

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