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eF-site ID
|
5vwq-J |
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PDB Code
|
5vwq |
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Chain
|
J |
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click to enlarge
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Title
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E.coli Aspartate aminotransferase-(1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP) |
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Classification
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TRANSFERASE |
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Compound
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Aspartate aminotransferase |
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Source
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Escherichia coli (strain K12) (AAT_ECOLI) |
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Sequence
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J: |
MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDET
GKTPVLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQE
LLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNTSV
KRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQL
SVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAMHKELIV
ASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIR
ANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQR
MRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVLR
LREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL
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Description
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Functional site
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|
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1)
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chain |
J |
| residue |
65 |
| type |
|
| sequence |
Y
|
| description |
binding site for residue PMP G 401
|
| source |
: AC3
|
|
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2)
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chain |
J |
| residue |
102 |
| type |
|
| sequence |
G
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
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3)
|
chain |
J |
| residue |
103 |
| type |
|
| sequence |
G
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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4)
|
chain |
J |
| residue |
104 |
| type |
|
| sequence |
T
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
|
5)
|
chain |
J |
| residue |
130 |
| type |
|
| sequence |
W
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
|
6)
|
chain |
J |
| residue |
183 |
| type |
|
| sequence |
N
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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7)
|
chain |
J |
| residue |
211 |
| type |
|
| sequence |
D
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
|
8)
|
chain |
J |
| residue |
214 |
| type |
|
| sequence |
Y
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
|
9)
|
chain |
J |
| residue |
243 |
| type |
|
| sequence |
S
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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10)
|
chain |
J |
| residue |
245 |
| type |
|
| sequence |
S
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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11)
|
chain |
J |
| residue |
246 |
| type |
|
| sequence |
K
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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12)
|
chain |
J |
| residue |
254 |
| type |
|
| sequence |
R
|
| description |
binding site for residue PMP J 401
|
| source |
: AC4
|
|
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13)
|
chain |
J |
| residue |
130 |
| type |
catalytic |
| sequence |
W
|
| description |
777
|
| source |
MCSA : MCSA4
|
|
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14)
|
chain |
J |
| residue |
211 |
| type |
catalytic |
| sequence |
D
|
| description |
777
|
| source |
MCSA : MCSA4
|
|
|
15)
|
chain |
J |
| residue |
246 |
| type |
catalytic |
| sequence |
K
|
| description |
777
|
| source |
MCSA : MCSA4
|
|
|
16)
|
chain |
J |
| residue |
34 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0007744|PDB:1ART, ECO:0007744|PDB:1CZE, ECO:0007744|PDB:3QPG, ECO:0007744|PDB:4DBC
|
| source |
Swiss-Prot : SWS_FT_FI1
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|
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17)
|
chain |
J |
| residue |
130 |
| type |
BINDING |
| sequence |
W
|
| description |
BINDING => ECO:0007744|PDB:1AIB, ECO:0007744|PDB:1ART, ECO:0007744|PDB:1CZE, ECO:0007744|PDB:1SPA, ECO:0007744|PDB:3QPG, ECO:0007744|PDB:4DBC
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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18)
|
chain |
J |
| residue |
183 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0007744|PDB:1AIB, ECO:0007744|PDB:1ART, ECO:0007744|PDB:1ASC, ECO:0007744|PDB:1CZE, ECO:0007744|PDB:1SPA, ECO:0007744|PDB:3QPG, ECO:0007744|PDB:4DBC
|
| source |
Swiss-Prot : SWS_FT_FI3
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|
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19)
|
chain |
J |
| residue |
374 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0007744|PDB:1AHG, ECO:0007744|PDB:1AIB, ECO:0007744|PDB:1ARG, ECO:0007744|PDB:1ART, ECO:0007744|PDB:1CZE, ECO:0007744|PDB:3QPG, ECO:0007744|PDB:4DBC
|
| source |
Swiss-Prot : SWS_FT_FI4
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|
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20)
|
chain |
J |
| residue |
246 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:11148029, ECO:0000269|PubMed:1993208, ECO:0000269|PubMed:3298240, ECO:0000269|PubMed:9891001, ECO:0007744|PDB:1AAW, ECO:0007744|PDB:1AHE, ECO:0007744|PDB:1AHF, ECO:0007744|PDB:1AHX, ECO:0007744|PDB:1AHY, ECO:0007744|PDB:1ARI, ECO:0007744|PDB:1ARS, ECO:0007744|PDB:1ASA, ECO:0007744|PDB:1ASB, ECO:0007744|PDB:1ASD, ECO:0007744|PDB:1ASE, ECO:0007744|PDB:1ASF, ECO:0007744|PDB:1ASG, ECO:0007744|PDB:1ASM, ECO:0007744|PDB:1ASN, ECO:0007744|PDB:1B4X, ECO:0007744|PDB:1CZC, ECO:0007744|PDB:1CZE, ECO:0007744|PDB:1G4V, ECO:0007744|PDB:1G4X, ECO:0007744|PDB:1G7W, ECO:0007744|PDB:1G7X, ECO:0007744|PDB:1IX6, ECO:0007744|PDB:1IX7, ECO:0007744|PDB:1IX8, ECO:0007744|PDB:1QIR, ECO:0007744|PDB:1QIS, ECO:0007744|PDB:1QIT, ECO:0007744|PDB:1YOO, ECO:0007744|PDB:2D5Y, ECO:0007744|PDB:2D61, ECO:0007744|PDB:2D63, ECO:0007744|PDB:2D7Y, ECO:0007744|PDB:3AAT, ECO:0007744|PDB:3ZZJ, ECO:0007744|PDB:5EAA
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| source |
Swiss-Prot : SWS_FT_FI5
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