eF-site ID 5vsm-AB PDB Code 5vsm Chain A, B click to enlarge Title Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine Classification ANTIVIRAL PROTEIN Compound Radical S-adenosyl methionine domain-containing protein 2 Source (RSAD2_MOUSE) Sequence A:  VSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLL KQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSV SIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIG RGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDED MNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLIS NEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLN CTDPSKSILDVGVEEAIK B:  VNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQ AGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSI VSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRG QGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMN EHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNE EFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCT PSKSILDVGVEEA Description Functional site 1) chain A residue 84 type sequence C description binding site for residue SF4 A 401 source : AC1 2) chain A residue 88 type sequence C description binding site for residue SF4 A 401 source : AC1 3) chain A residue 91 type sequence C description binding site for residue SF4 A 401 source : AC1 4) chain A residue 126 type sequence G description binding site for residue SF4 A 401 source : AC1 5) chain A residue 158 type sequence N description binding site for residue SF4 A 401 source : AC1 6) chain A residue 194 type sequence R description binding site for residue SF4 A 401 source : AC1 7) chain A residue 90 type sequence F description binding site for residue 5AD A 402 source : AC2 8) chain A residue 92 type sequence F description binding site for residue 5AD A 402 source : AC2 9) chain A residue 180 type sequence S description binding site for residue 5AD A 402 source : AC2 10) chain A residue 194 type sequence R description binding site for residue 5AD A 402 source : AC2 11) chain A residue 222 type sequence N description binding site for residue 5AD A 402 source : AC2 12) chain A residue 224 type sequence V description binding site for residue 5AD A 402 source : AC2 13) chain A residue 250 type sequence Q description binding site for residue 5AD A 402 source : AC2 14) chain A residue 251 type sequence C description binding site for residue 5AD A 402 source : AC2 15) chain A residue 252 type sequence L description binding site for residue 5AD A 402 source : AC2 16) chain A residue 258 type sequence N description binding site for residue 5AD A 402 source : AC2 17) chain A residue 124 type sequence S description binding site for residue MET A 403 source : AC3 18) chain A residue 125 type sequence G description binding site for residue MET A 403 source : AC3 19) chain A residue 126 type sequence G description binding site for residue MET A 403 source : AC3 20) chain A residue 127 type sequence E description binding site for residue MET A 403 source : AC3 21) chain A residue 156 type sequence V description binding site for residue MET A 403 source : AC3 22) chain A residue 157 type sequence S description binding site for residue MET A 403 source : AC3 23) chain A residue 158 type sequence N description binding site for residue MET A 403 source : AC3 24) chain A residue 180 type sequence S description binding site for residue MET A 403 source : AC3 25) chain A residue 194 type sequence R description binding site for residue MET A 403 source : AC3 26) chain B residue 84 type sequence C description binding site for residue SF4 B 401 source : AC4 27) chain B residue 88 type sequence C description binding site for residue SF4 B 401 source : AC4 28) chain B residue 91 type sequence C description binding site for residue SF4 B 401 source : AC4 29) chain B residue 126 type sequence G description binding site for residue SF4 B 401 source : AC4 30) chain B residue 158 type sequence N description binding site for residue SF4 B 401 source : AC4 31) chain B residue 194 type sequence R description binding site for residue SF4 B 401 source : AC4 32) chain B residue 265 type sequence R description binding site for residue SF4 B 401 source : AC4 33) chain B residue 90 type sequence F description binding site for residue 5AD B 402 source : AC5 34) chain B residue 92 type sequence F description binding site for residue 5AD B 402 source : AC5 35) chain B residue 180 type sequence S description binding site for residue 5AD B 402 source : AC5 36) chain B residue 194 type sequence R description binding site for residue 5AD B 402 source : AC5 37) chain B residue 222 type sequence N description binding site for residue 5AD B 402 source : AC5 38) chain B residue 224 type sequence V description binding site for residue 5AD B 402 source : AC5 39) chain B residue 249 type sequence F description binding site for residue 5AD B 402 source : AC5 40) chain B residue 250 type sequence Q description binding site for residue 5AD B 402 source : AC5 41) chain B residue 251 type sequence C description binding site for residue 5AD B 402 source : AC5 42) chain B residue 252 type sequence L description binding site for residue 5AD B 402 source : AC5 43) chain B residue 258 type sequence N description binding site for residue 5AD B 402 source : AC5 44) chain B residue 92 type sequence F description binding site for residue MET B 403 source : AC6 45) chain B residue 124 type sequence S description binding site for residue MET B 403 source : AC6 46) chain B residue 125 type sequence G description binding site for residue MET B 403 source : AC6 47) chain B residue 126 type sequence G description binding site for residue MET B 403 source : AC6 48) chain B residue 127 type sequence E description binding site for residue MET B 403 source : AC6 49) chain B residue 156 type sequence V description binding site for residue MET B 403 source : AC6 50) chain B residue 157 type sequence S description binding site for residue MET B 403 source : AC6 51) chain B residue 158 type sequence N description binding site for residue MET B 403 source : AC6 52) chain B residue 180 type sequence S description binding site for residue MET B 403 source : AC6 53) chain B residue 194 type sequence R description binding site for residue MET B 403 source : AC6 54) chain A residue 84 type catalytic sequence C description 965 source MCSA : MCSA1 55) chain A residue 88 type catalytic sequence C description 965 source MCSA : MCSA1 56) chain A residue 91 type catalytic sequence C description 965 source MCSA : MCSA1 57) chain B residue 84 type catalytic sequence C description 965 source MCSA : MCSA2 58) chain B residue 88 type catalytic sequence C description 965 source MCSA : MCSA2 59) chain B residue 91 type catalytic sequence C description 965 source MCSA : MCSA2 60) chain A residue 84 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 61) chain A residue 88 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 62) chain A residue 91 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 63) chain B residue 84 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 64) chain B residue 88 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 65) chain B residue 91 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28607080, ECO:0007744|PDB:5VSL, ECO:0007744|PDB:5VSM source Swiss-Prot : SWS_FT_FI1 66) chain A residue 198 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q8WXG1 source Swiss-Prot : SWS_FT_FI2 67) chain B residue 198 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q8WXG1 source Swiss-Prot : SWS_FT_FI2 68) chain A residue 207 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q8WXG1 source Swiss-Prot : SWS_FT_FI3 69) chain B residue 207 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q8WXG1 source Swiss-Prot : SWS_FT_FI3

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