eF-site ID 5vk0-ACEGIKMOQSUW PDB Code 5vk0 Chain A, C, E, G, I, K, M, O, Q, S, U, W click to enlarge Title Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI Classification LIGASE/LIGASE INHIBITOR Compound E3 ubiquitin-protein ligase Mdm2 Source (5VK0) Sequence A:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV C:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV E:  TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKR LYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYR NLV G:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV I:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV K:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV M:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV O:  TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKR LYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYR NLV Q:  TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKR LYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYR NLV S:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLVV U:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLV W:  ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY RNLV Description Functional site 1) chain C residue 33 type sequence L description binding site for residue CL C 201 source : AC1

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