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eF-site ID
|
5vhi-f |
|
PDB Code
|
5vhi |
|
Chain
|
f |
|
click to enlarge
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Title
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Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle |
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Classification
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HYDROLASE |
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Compound
|
26S proteasome regulatory subunit 7 |
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Source
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(PSMD2_HUMAN) |
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Sequence
|
f: |
RDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQEL
SEEDKQLQDELYRPALEELRRQIRSSTTSMTSVPKPLKFL
RPHYNKRFAADIISVLAMTMSGERECLKYRLVGAGEVAKE
WQELDDAEKVQREPLLTLVKEIVPLLMEIEQVDMLEKDID
ENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRF
PEALRLALMLNDMELVEDIFTSCKDVVMLGRHGVFLELSE
DVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIY
KTHLENNRFGGSGSQVDSARMNLASSFVNGFVNQDKLLTD
DGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYL
YSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHN
SNTMRLGSIFGLGLAYNREDVLTLLLPVMGDSKSSMEVAG
VTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYAR
WLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVD
VCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKD
KDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFG
HLLRYGEPTLRRAVPLALALISVSHDADPEVSYNSIFAAR
LAAMLRQLAQYHAKKGTLTLCPYHSDRQLMSQVAVAGLLT
VLVSFL
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Description
|
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Functional site
|
|
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1)
|
chain |
f |
| residue |
24 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0007744|PubMed:17323924, ECO:0007744|PubMed:20068231
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
f |
| residue |
361 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
3)
|
chain |
f |
| residue |
363 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
4)
|
chain |
f |
| residue |
551 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:Q8VDM4
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
5)
|
chain |
f |
| residue |
16 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:17323924, ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
f |
| residue |
29 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:17323924
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|