eF-site ID 5vfr-A
PDB Code 5vfr
Chain A

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Title Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Classification HYDROLASE
Compound 26S proteasome non-ATPase regulatory subunit 1
Source (PSMD2_HUMAN)
Sequence A:  AADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK
FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPT
VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKG
VLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVG
EGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGG
DNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPAL
MRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFE
LLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLE
AVNKVIKSYAKFSATPRYMTYN
Description (1)  Activated Human 26S Proteasome


Functional site

1) chain A
residue 179
type
sequence G
description binding site for residue AGS A 501
source : AC2

2) chain A
residue 218
type
sequence P
description binding site for residue AGS A 501
source : AC2

3) chain A
residue 219
type
sequence G
description binding site for residue AGS A 501
source : AC2

4) chain A
residue 220
type
sequence T
description binding site for residue AGS A 501
source : AC2

5) chain A
residue 221
type
sequence G
description binding site for residue AGS A 501
source : AC2

6) chain A
residue 222
type
sequence K
description binding site for residue AGS A 501
source : AC2

7) chain A
residue 223
type
sequence T
description binding site for residue AGS A 501
source : AC2

8) chain A
residue 224
type
sequence L
description binding site for residue AGS A 501
source : AC2

9) chain A
residue 275
type
sequence D
description binding site for residue AGS A 501
source : AC2

10) chain A
residue 354
type
sequence I
description binding site for residue AGS A 501
source : AC2

11) chain A
residue 357
type
sequence I
description binding site for residue AGS A 501
source : AC2

12) chain A
residue 358
type
sequence H
description binding site for residue AGS A 501
source : AC2

13) chain A
residue 382
type
sequence G
description binding site for residue AGS A 501
source : AC2

14) chain A
residue 383
type
sequence A
description binding site for residue AGS A 501
source : AC2

15) chain A
residue 315-333
type prosite
sequence IKVLMATNRPDTLDPALMR
description AAA AAA-protein family signature. VkMImATNrpdtLDpALl.R
source prosite : PS00674


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