eF-site ID 5v59-A PDB Code 5v59 Chain A click to enlarge Title Crystal structure of catalytic fragment of human AlaRS in complex with Aze-SA Classification LIGASE Compound Alanine--tRNA ligase, cytoplasmic Source (SYAC_HUMAN) Sequence A:  TLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFAN AGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGNDL DDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQE FGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTK ILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVN QDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLE RLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGA EDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLR RILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELK KDPDMVKDIINEEEVQFLK Description Functional site 1) chain A residue 77 type sequence R description binding site for residue 8X1 A 501 source : AC1 2) chain A residue 93 type sequence Y description binding site for residue 8X1 A 501 source : AC1 3) chain A residue 94 type sequence H description binding site for residue 8X1 A 501 source : AC1 4) chain A residue 95 type sequence H description binding site for residue 8X1 A 501 source : AC1 5) chain A residue 98 type sequence F description binding site for residue 8X1 A 501 source : AC1 6) chain A residue 100 type sequence M description binding site for residue 8X1 A 501 source : AC1 7) chain A residue 176 type sequence W description binding site for residue 8X1 A 501 source : AC1 8) chain A residue 213 type sequence E description binding site for residue 8X1 A 501 source : AC1 9) chain A residue 214 type sequence I description binding site for residue 8X1 A 501 source : AC1 10) chain A residue 216 type sequence N description binding site for residue 8X1 A 501 source : AC1 11) chain A residue 218 type sequence V description binding site for residue 8X1 A 501 source : AC1 12) chain A residue 239 type sequence D description binding site for residue 8X1 A 501 source : AC1 13) chain A residue 240 type sequence T description binding site for residue 8X1 A 501 source : AC1 14) chain A residue 241 type sequence G description binding site for residue 8X1 A 501 source : AC1 15) chain A residue 243 type sequence G description binding site for residue 8X1 A 501 source : AC1 16) chain A residue 246 type sequence R description binding site for residue 8X1 A 501 source : AC1 17) chain A residue 8 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI3 18) chain A residue 19 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4 19) chain A residue 95 type BINDING sequence H description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 20) chain A residue 176 type BINDING sequence W description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 21) chain A residue 214 type BINDING sequence I description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 22) chain A residue 216 type BINDING sequence N description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 23) chain A residue 239 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 24) chain A residue 243 type BINDING sequence G description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1 25) chain A residue 77 type BINDING sequence R description BINDING => ECO:0000269|PubMed:27622773, ECO:0000269|Ref.24, ECO:0007744|PDB:4XEM, ECO:0007744|PDB:4XEO, ECO:0007744|PDB:5KNN source Swiss-Prot : SWS_FT_FI1

Display surface Download Links