eF-site ID 5v48-B PDB Code 5v48 Chain B click to enlarge Title Soluble rabbit neprilysin in complex with thiorphan Classification HYDROLASE Compound Neprilysin Source (NEP_RABIT) Sequence B:  GICKSSDCIKSAARLIQNMDATAEPCTDFFKYACGGWLKR NVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQ KAKTLYRSCVNETAIDSRGGQPLLKLLPDVYGWPVATQNW EQTYGTSWSAEKSIAQLNSKYGKKVLINFFVGTDDKNSMN HIIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMIAVAK LIRQEEGLPIDENQISVEMNKVMELEKEIANATTKSEDRN DPMLLYNKMTLAQIQNNFSLEINGKPFSWSNFTNEIMSTV NINIPNEEDVVVYAPEYLIKLKPILTKYSPRDLQNLMSWR FIMDLVSSLSRTYKDSRNAFRKALYGTTSESATWRRCANY VNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQT LDDLTWMDAETKKKAEEKALAIKERIGYPDDIVSNDNKLN NEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE WITGAAIVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLN YGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANN FKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG IGQAYRAYQNYVKKNGEEKLLPGIDLNHKQLFFLNFAQVW CGTYRPEYAVNSIKTDVHSPGNFRIIGSLQNSVEFSEAFQ CPKNSYMNPEKKCRVW Description Functional site 1) chain B residue 585 type ACT_SITE sequence E description ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01233, ECO:0000255|PROSITE-ProRule:PRU10095 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 651 type ACT_SITE sequence D description Proton donor => ECO:0000255|PROSITE-ProRule:PRU01233 source Swiss-Prot : SWS_FT_FI2 3) chain B residue 103 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:P07861 source Swiss-Prot : SWS_FT_FI3 4) chain B residue 628 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI8 5) chain B residue 584 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU01233, ECO:0000305|PubMed:3162886 source Swiss-Prot : SWS_FT_FI4 6) chain B residue 588 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU01233, ECO:0000305|PubMed:3162886 source Swiss-Prot : SWS_FT_FI4 7) chain B residue 647 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01233 source Swiss-Prot : SWS_FT_FI5 8) chain B residue 145 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250|UniProtKB:P08473 source Swiss-Prot : SWS_FT_FI6 9) chain B residue 311 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250|UniProtKB:P08473 source Swiss-Prot : SWS_FT_FI6 10) chain B residue 325 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250|UniProtKB:P08473 source Swiss-Prot : SWS_FT_FI6 11) chain B residue 285 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI7

Display surface Download Links