eF-site ID 5uvi-A PDB Code 5uvi Chain A click to enlarge Title Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation Classification MEMBRANE PROTEIN Compound Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a Source (AA2AR_HUMAN) Sequence A:  DGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNL QNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGC LFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQ GCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVY LRIFLAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDA LTKMRAAALDAQKADFRHGFDILVGQIDDALKLANEGKVK EAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSLAI IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLS HTNSVVNPFIYAYRIREFRQTFRKIIRSHVL Description Functional site 1) chain A residue 168 type sequence F description binding site for residue ZMA A 1201 source : AC1 2) chain A residue 169 type sequence E description binding site for residue ZMA A 1201 source : AC1 3) chain A residue 177 type sequence M description binding site for residue ZMA A 1201 source : AC1 4) chain A residue 246 type sequence W description binding site for residue ZMA A 1201 source : AC1 5) chain A residue 249 type sequence L description binding site for residue ZMA A 1201 source : AC1 6) chain A residue 250 type sequence H description binding site for residue ZMA A 1201 source : AC1 7) chain A residue 253 type sequence N description binding site for residue ZMA A 1201 source : AC1 8) chain A residue 267 type sequence L description binding site for residue ZMA A 1201 source : AC1 9) chain A residue 270 type sequence M description binding site for residue ZMA A 1201 source : AC1 10) chain A residue 255 type sequence F description binding site for residue CLR A 1202 source : AC2 11) chain A residue 258 type sequence F description binding site for residue CLR A 1202 source : AC2 12) chain A residue 259 type sequence C description binding site for residue CLR A 1202 source : AC2 13) chain A residue 251 type sequence I description binding site for residue CLR A 1203 source : AC3 14) chain A residue 262 type sequence C description binding site for residue CLR A 1203 source : AC3 15) chain A residue 263 type sequence S description binding site for residue CLR A 1203 source : AC3 16) chain A residue 265 type sequence A description binding site for residue CLR A 1203 source : AC3 17) chain A residue 58 type sequence L description binding site for residue CLR A 1204 source : AC4 18) chain A residue 72 type sequence A description binding site for residue CLR A 1204 source : AC4 19) chain A residue 73 type sequence A description binding site for residue CLR A 1204 source : AC4 20) chain A residue 76 type sequence G description binding site for residue CLR A 1204 source : AC4 21) chain A residue 80 type sequence I description binding site for residue CLR A 1204 source : AC4 22) chain A residue 125 type sequence I description binding site for residue OLC A 1205 source : AC5 23) chain A residue 129 type sequence W description binding site for residue OLC A 1205 source : AC5 24) chain A residue 6 type sequence S description binding site for residue OLC A 1206 source : AC6 25) chain A residue 271 type sequence Y description binding site for residue OLC A 1206 source : AC6 26) chain A residue 7 type sequence S description binding site for residue OLA A 1207 source : AC7 27) chain A residue 11 type sequence T description binding site for residue OLA A 1207 source : AC7 28) chain A residue 8-32 type TRANSMEM sequence VYITVELAIAVLAILGNVLVCWAVW description Helical; Name=1 source Swiss-Prot : SWS_FT_FI1 29) chain A residue 43-66 type TRANSMEM sequence YFVVSLAAADIAVGVLAIPFAITI description Helical; Name=2 source Swiss-Prot : SWS_FT_FI3 30) chain A residue 78-100 type TRANSMEM sequence LFIACFVLVLTQSSIFSLLAIAI description Helical; Name=3 source Swiss-Prot : SWS_FT_FI5 31) chain A residue 121-143 type TRANSMEM sequence AKGIIAICWVLSFAIGLTPMLGW description Helical; Name=4 source Swiss-Prot : SWS_FT_FI6 32) chain A residue 174-198 type TRANSMEM sequence MNYMVYFNFFACVLVPLLLMLGVYL description Helical; Name=5 source Swiss-Prot : SWS_FT_FI7 33) chain A residue 169 type BINDING sequence E description BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO source Swiss-Prot : SWS_FT_FI10 34) chain A residue 253 type BINDING sequence N description BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO source Swiss-Prot : SWS_FT_FI10 35) chain A residue 277 type BINDING sequence S description BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO source Swiss-Prot : SWS_FT_FI10 36) chain A residue 278 type BINDING sequence H description BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO source Swiss-Prot : SWS_FT_FI10 37) chain A residue 154 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI11 38) chain A residue 235-258 type TRANSMEM sequence LAIIVGLFALCWLPLHIINCFTFF description Helical; Name=6 source Swiss-Prot : SWS_FT_FI8 39) chain A residue 267-290 type TRANSMEM sequence LWLMYLAIVLSHTNSVVNPFIYAY description Helical; Name=7 source Swiss-Prot : SWS_FT_FI9 40) chain A residue 90-106 type prosite sequence SSIFSLLAIAIDRYIAI description G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIfSLLAIAIDRYIaI source prosite : PS00237 41) chain A residue 33-42 type TOPO_DOM sequence LNSNLQNVTN description Cytoplasmic => ECO:0000269|PubMed:18832607 source Swiss-Prot : SWS_FT_FI2 42) chain A residue 101-120 type TOPO_DOM sequence DRYIAIRIPLRYNGLVTGTR description Cytoplasmic => ECO:0000269|PubMed:18832607 source Swiss-Prot : SWS_FT_FI2 43) chain A residue 67-77 type TOPO_DOM sequence STGFCAACHGC description Extracellular => ECO:0000269|PubMed:18832607 source Swiss-Prot : SWS_FT_FI4 44) chain A residue 144-173 type TOPO_DOM sequence NNCGQPKEGKNHSQGCGEGQVACLFEDVVP description Extracellular => ECO:0000269|PubMed:18832607 source Swiss-Prot : SWS_FT_FI4 45) chain A residue 259-266 type TOPO_DOM sequence CPDCSHAP description Extracellular => ECO:0000269|PubMed:18832607 source Swiss-Prot : SWS_FT_FI4 46) chain A residue 1007 type BINDING sequence W description axial binding residue source Swiss-Prot : SWS_FT_FI12 47) chain A residue 1102 type BINDING sequence I description axial binding residue source Swiss-Prot : SWS_FT_FI12

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