eF-site ID 5uru-EFGH PDB Code 5uru Chain E, F, G, H click to enlarge Title Insulin with proline analog DhP at position B28 in the R6 state Classification HORMONE Compound Insulin Chain A Source (INS_HUMAN) Sequence E:  GIVEQCCTSICSLYQLENYCN F:  VNQHLCGSHLVEALYLVCGERGFFYTX G:  GIVEQCCTSICSLYQLENYCN H:  FVNQHLCGSHLVEALYLVCGERGFFYTX Description Functional site 1) chain E residue 6 type sequence C description binding site for residue IPH E 101 source : AC7 2) chain E residue 11 type sequence C description binding site for residue IPH E 101 source : AC7 3) chain F residue 11 type sequence L description binding site for residue IPH E 101 source : AC7 4) chain F residue 10 type sequence H description binding site for residue ZN F 101 source : AC8 5) chain F residue 10 type sequence H description binding site for residue ZN F 101 source : AC8 6) chain F residue 10 type sequence H description binding site for residue ZN F 101 source : AC8 7) chain F residue 10 type sequence H description binding site for residue CL F 102 source : AC9 8) chain F residue 10 type sequence H description binding site for residue CL F 102 source : AC9 9) chain F residue 10 type sequence H description binding site for residue CL F 102 source : AC9 10) chain G residue 6 type sequence C description binding site for residue IPH G 101 source : AD1 11) chain G residue 9 type sequence S description binding site for residue IPH G 101 source : AD1 12) chain G residue 10 type sequence I description binding site for residue IPH G 101 source : AD1 13) chain G residue 11 type sequence C description binding site for residue IPH G 101 source : AD1 14) chain H residue 5 type sequence H description binding site for residue IPH G 101 source : AD1 15) chain H residue 11 type sequence L description binding site for residue IPH G 101 source : AD1 16) chain H residue 10 type sequence H description binding site for residue ZN H 101 source : AD2 17) chain H residue 10 type sequence H description binding site for residue ZN H 101 source : AD2 18) chain H residue 10 type sequence H description binding site for residue ZN H 101 source : AD2 19) chain H residue 6 type sequence L description binding site for residue CL H 102 source : AD3 20) chain H residue 10 type sequence H description binding site for residue CL H 102 source : AD3 21) chain H residue 10 type sequence H description binding site for residue CL H 102 source : AD3 22) chain H residue 10 type sequence H description binding site for residue CL H 102 source : AD3

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