|
|
eF-site ID
|
5umd-i |
|
PDB Code
|
5umd |
|
Chain
|
i |
|
click to enlarge
|
|
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Title
|
Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine |
|
Classification
|
RIBOSOME |
|
Compound
|
28S ribosomal RNA |
|
Source
|
ORGANISM_SCIENTIFIC: Plasmodium falciparum 3D7; |
|
|
Sequence
|
i: |
VNVPKTRKTYCSNKCKKHTMHKVSQYKKGKERLSSLGRRR
YDMKQKGFGGQTKPVFKKKAKTTKKIVLKLECTKCKKKRF
QTMKRCKTFEMGADK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
i |
| residue |
12 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN i 201
|
| source |
: AT6
|
|
|
2)
|
chain |
i |
| residue |
14 |
| type |
|
| sequence |
N
|
| description |
binding site for residue ZN i 201
|
| source |
: AT6
|
|
|
3)
|
chain |
i |
| residue |
16 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN i 201
|
| source |
: AT6
|
|
|
4)
|
chain |
i |
| residue |
73 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN i 201
|
| source |
: AT6
|
|
|
5)
|
chain |
i |
| residue |
76 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN i 201
|
| source |
: AT6
|
|
|
6)
|
chain |
i |
| residue |
62-73 |
| type |
prosite |
| sequence |
KTTKKIVLKLEC
|
| description |
RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLKleC
|
| source |
prosite : PS01172
|
|
|
|