|
|
eF-site ID
|
5umd-c |
|
PDB Code
|
5umd |
|
Chain
|
c |
|
click to enlarge
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Title
|
Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine |
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Classification
|
RIBOSOME |
|
Compound
|
28S ribosomal RNA |
|
Source
|
ORGANISM_SCIENTIFIC: Plasmodium falciparum 3D7; |
|
|
Sequence
|
c: |
GKAGKGTGSFGKRNGKTHFLCLRCGKRSYHLQKKKCASCG
YPSAKKRRFNWSVKAKRRNTTGTGRCRYIKTLRRKLKNKF
TEGSTPKPK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
c |
| residue |
33 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue MG A 3932
|
| source |
: AP5
|
|
|
2)
|
chain |
c |
| residue |
22 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN c 101
|
| source |
: AT3
|
|
|
3)
|
chain |
c |
| residue |
25 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN c 101
|
| source |
: AT3
|
|
|
4)
|
chain |
c |
| residue |
37 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN c 101
|
| source |
: AT3
|
|
|
5)
|
chain |
c |
| residue |
40 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN c 101
|
| source |
: AT3
|
|
|
6)
|
chain |
c |
| residue |
7-26 |
| type |
prosite |
| sequence |
GTGSFGKRNGKTHFLCLRCG
|
| description |
RIBOSOMAL_L37E Ribosomal protein L37e signature. GTgSfGkRngkt.HflClRCG
|
| source |
prosite : PS01077
|
|
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|