eF-site ID 5q08-E PDB Code 5q08 Chain E click to enlarge Title Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(1-benzothiophen-3-ylsulfonyl)-3-(5-bromo-1,3-thiazol-2-yl)urea Classification HYDROLASE/HYDROLASE INHIBITOR Compound Fructose-1,6-bisphosphatase 1 Source (Q2TU34_HUMAN) Sequence E:  DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAV RKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVS EEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIF GIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLA MDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYA KDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTL VYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMAT TGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS Description Functional site 1) chain E residue 17 type sequence V description binding site for residue 967 E 401 source : AC5 2) chain E residue 21 type sequence G description binding site for residue 967 E 401 source : AC5 3) chain E residue 22 type sequence R description binding site for residue 967 E 401 source : AC5 4) chain E residue 24 type sequence A description binding site for residue 967 E 401 source : AC5 5) chain E residue 26 type sequence G description binding site for residue 967 E 401 source : AC5 6) chain E residue 27 type sequence T description binding site for residue 967 E 401 source : AC5 7) chain E residue 28 type sequence G description binding site for residue 967 E 401 source : AC5 8) chain E residue 29 type sequence E description binding site for residue 967 E 401 source : AC5 9) chain E residue 30 type sequence L description binding site for residue 967 E 401 source : AC5 10) chain E residue 31 type sequence T description binding site for residue 967 E 401 source : AC5 11) chain E residue 27 type sequence T description binding site for residue 967 G 401 source : AC7 12) chain E residue 28 type sequence G description binding site for residue 967 G 401 source : AC7

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