eF-site ID 5q05-D PDB Code 5q05 Chain D click to enlarge Title Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylurea Classification Hydrolase/Hydrolase Inhibitor Compound Fructose-1,6-bisphosphatase 1 Source (Q2TU34_HUMAN) Sequence D:  DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAV RKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEE DKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGI YRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMD CGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKD FDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVY GGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTG KEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS Description Functional site 1) chain D residue 27 type sequence T description binding site for residue 95S B 401 source : AC2 2) chain D residue 28 type sequence G description binding site for residue 95S B 401 source : AC2 3) chain D residue 21 type sequence G description binding site for residue 95S D 401 source : AC4 4) chain D residue 22 type sequence R description binding site for residue 95S D 401 source : AC4 5) chain D residue 26 type sequence G description binding site for residue 95S D 401 source : AC4 6) chain D residue 27 type sequence T description binding site for residue 95S D 401 source : AC4 7) chain D residue 28 type sequence G description binding site for residue 95S D 401 source : AC4 8) chain D residue 29 type sequence E description binding site for residue 95S D 401 source : AC4 9) chain D residue 30 type sequence L description binding site for residue 95S D 401 source : AC4 10) chain D residue 31 type sequence T description binding site for residue 95S D 401 source : AC4 11) chain D residue 160 type sequence V description binding site for residue 95S D 401 source : AC4

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