eF-site ID 5pzt-C
PDB Code 5pzt
Chain C

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Title Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(3-ethyl-4-phenylphenyl)sulfonylurea
Classification HYDROLASE/HYDROLASE INHIBITOR
Compound Fructose-1,6-bisphosphatase 1
Source (Q2TU34_HUMAN)
Sequence C:  DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAV
RKAGIAKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIV
EPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTD
EPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFM
LDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTE
YIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYP
ANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDV
IPTDIHQRAPVILGSPDDVLEFLKVYEKHS
Description


Functional site

1) chain C
residue 17
type
sequence V
description binding site for residue 947 C 401
source : AC3

2) chain C
residue 20
type
sequence E
description binding site for residue 947 C 401
source : AC3

3) chain C
residue 21
type
sequence G
description binding site for residue 947 C 401
source : AC3

4) chain C
residue 22
type
sequence R
description binding site for residue 947 C 401
source : AC3

5) chain C
residue 24
type
sequence A
description binding site for residue 947 C 401
source : AC3

6) chain C
residue 26
type
sequence G
description binding site for residue 947 C 401
source : AC3

7) chain C
residue 27
type
sequence T
description binding site for residue 947 C 401
source : AC3

8) chain C
residue 28
type
sequence G
description binding site for residue 947 C 401
source : AC3

9) chain C
residue 29
type
sequence E
description binding site for residue 947 C 401
source : AC3

10) chain C
residue 30
type
sequence L
description binding site for residue 947 C 401
source : AC3

11) chain C
residue 31
type
sequence T
description binding site for residue 947 C 401
source : AC3


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