eF-site ID 5pzr-D
PDB Code 5pzr
Chain D

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Title Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[3-[3-[(3-chlorophenyl)sulfonylcarbamoylamino]propoxy]propyl]urea
Classification HYDROLASE/HYDROLASE inhibitor
Compound Fructose-1,6-bisphosphatase 1
Source (Q2TU34_HUMAN)
Sequence D:  DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAV
RKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEE
DKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGI
YRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMD
CGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKD
FDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVY
GGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTG
KEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS
Description


Functional site

1) chain D
residue 17
type
sequence V
description binding site for residue 93S B 401
source : AC2

2) chain D
residue 18
type
sequence M
description binding site for residue 93S B 401
source : AC2

3) chain D
residue 21
type
sequence G
description binding site for residue 93S B 401
source : AC2

4) chain D
residue 22
type
sequence R
description binding site for residue 93S B 401
source : AC2

5) chain D
residue 26
type
sequence G
description binding site for residue 93S B 401
source : AC2

6) chain D
residue 27
type
sequence T
description binding site for residue 93S B 401
source : AC2

7) chain D
residue 28
type
sequence G
description binding site for residue 93S B 401
source : AC2

8) chain D
residue 29
type
sequence E
description binding site for residue 93S B 401
source : AC2

9) chain D
residue 30
type
sequence L
description binding site for residue 93S B 401
source : AC2

10) chain D
residue 31
type
sequence T
description binding site for residue 93S B 401
source : AC2


Display surface

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