|
|
eF-site ID
|
5pep-A |
|
PDB Code
|
5pep |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
X-RAY ANALYSES OF ASPARTIC PROTEASES. II. THREE-DIMENSIONAL STRUCTURE OF THE HEXAGONAL CRYSTAL FORM OF PORCINE PEPSIN AT 2.3 ANGSTROMS RESOLUTION |
|
Classification
|
HYDROLASE(ACID PROTEINASE) |
|
Compound
|
PEPSIN |
|
Source
|
Sus scrofa (Pig) (PEPA_PIG) |
|
|
Sequence
|
A: |
IGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWV
PSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSM
TGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGI
LGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDD
SGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMD
GETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASEN
SDGEMVISCSSIASLPDIVFTINGVQYPLSPSAYILQDDD
SCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKV
GLAPVA
|
|
|
Description
|
(1) |
PEPSIN (E.C.3.4.23.1)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
32 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: CAT
|
|
|
2)
|
chain |
A |
| residue |
215 |
| type |
|
| sequence |
D
|
| description |
|
| source |
: CAT
|
|
|
3)
|
chain |
A |
| residue |
29-40 |
| type |
prosite |
| sequence |
VIFDTGSSNLWV
|
| description |
ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSSNLWV
|
| source |
prosite : PS00141
|
|
|
4)
|
chain |
A |
| residue |
212-223 |
| type |
prosite |
| sequence |
AIVDTGTSLLTG
|
| description |
ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSSNLWV
|
| source |
prosite : PS00141
|
|
|
5)
|
chain |
A |
| residue |
32 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10094, ECO:0000269|PubMed:1097438, ECO:0000269|PubMed:4897201
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
215 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10094, ECO:0000269|PubMed:1097438, ECO:0000269|PubMed:4897201
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
68 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P03954
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|