eF-site ID 5oww-B PDB Code 5oww Chain B click to enlarge Title Crystal structure of human BRD4(1) bromodomain in complex with UT22B Classification DNA BINDING PROTEIN Compound Bromodomain-containing protein 4 Source (BRD4_HUMAN) Sequence B:  SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAW PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI NELPTEE Description Functional site 1) chain B residue 81 type sequence W description binding site for residue B0Q B 201 source : AC2 2) chain B residue 82 type sequence P description binding site for residue B0Q B 201 source : AC2 3) chain B residue 85 type sequence Q description binding site for residue B0Q B 201 source : AC2 4) chain B residue 87 type sequence V description binding site for residue B0Q B 201 source : AC2 5) chain B residue 92 type sequence L description binding site for residue B0Q B 201 source : AC2 6) chain B residue 94 type sequence L description binding site for residue B0Q B 201 source : AC2 7) chain B residue 140 type sequence N description binding site for residue B0Q B 201 source : AC2 8) chain B residue 145 type sequence D description binding site for residue B0Q D 201 source : AC4 9) chain B residue 149 type sequence M description binding site for residue B0Q D 201 source : AC4 10) chain B residue 140 type SITE sequence N description Acetylated histone binding => ECO:0000269|PubMed:22464331 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 99 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI2

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