eF-site ID 5owt-B PDB Code 5owt Chain B click to enlarge Title Crystal structure of TNKS2 in complex with (5S)-5-methyl-5-[4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]imidazolidine-2,4-dione Classification TRANSFERASE Compound Tankyrase-2 Source (TNKS2_HUMAN) Sequence B:  GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNR YNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFH GSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQY VYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFS AMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLI TYQIMRPE Description Functional site 1) chain B residue 977 type sequence R description binding site for residue SO4 B 1201 source : AC5 2) chain B residue 979 type sequence H description binding site for residue SO4 B 1201 source : AC5 3) chain B residue 980 type sequence R description binding site for residue SO4 B 1201 source : AC5 4) chain B residue 1067 type sequence K description binding site for residue SO4 B 1201 source : AC5 5) chain B residue 1070 type sequence Q description binding site for residue SO4 B 1201 source : AC5 6) chain B residue 1113 type sequence M description binding site for residue SO4 B 1201 source : AC5 7) chain B residue 990 type sequence N description binding site for residue SO4 B 1202 source : AC6 8) chain B residue 991 type sequence R description binding site for residue SO4 B 1202 source : AC6 9) chain B residue 1158 type sequence M description binding site for residue SO4 B 1202 source : AC6 10) chain B residue 1160 type sequence P description binding site for residue SO4 B 1202 source : AC6 11) chain B residue 1161 type sequence E description binding site for residue SO4 B 1202 source : AC6 12) chain B residue 1031 type sequence H description binding site for residue F37 B 1203 source : AC7 13) chain B residue 1032 type sequence G description binding site for residue F37 B 1203 source : AC7 14) chain B residue 1033 type sequence S description binding site for residue F37 B 1203 source : AC7 15) chain B residue 1035 type sequence F description binding site for residue F37 B 1203 source : AC7 16) chain B residue 1047 type sequence R description binding site for residue F37 B 1203 source : AC7 17) chain B residue 1047 type sequence R description binding site for residue F37 B 1203 source : AC7 18) chain B residue 1048 type sequence H description binding site for residue F37 B 1203 source : AC7 19) chain B residue 1049 type sequence A description binding site for residue F37 B 1203 source : AC7 20) chain B residue 1050 type sequence Y description binding site for residue F37 B 1203 source : AC7 21) chain B residue 1060 type sequence Y description binding site for residue F37 B 1203 source : AC7 22) chain B residue 1067 type sequence K description binding site for residue F37 B 1203 source : AC7 23) chain B residue 1068 type sequence S description binding site for residue F37 B 1203 source : AC7 24) chain B residue 1071 type sequence Y description binding site for residue F37 B 1203 source : AC7 25) chain B residue 1138 type sequence E description binding site for residue F37 B 1203 source : AC7 26) chain B residue 1081 type sequence C description binding site for residue ZN B 1204 source : AC8 27) chain B residue 1084 type sequence H description binding site for residue ZN B 1204 source : AC8 28) chain B residue 1089 type sequence C description binding site for residue ZN B 1204 source : AC8 29) chain B residue 1092 type sequence C description binding site for residue ZN B 1204 source : AC8 30) chain B residue 1081 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 1084 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 32) chain B residue 1089 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 33) chain B residue 1092 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links