eF-site ID 5o5f-A PDB Code 5o5f Chain A click to enlarge Title Crystal structure of the human BRPF1 bromodomain in complex with BZ038 Classification DNA BINDING PROTEIN Compound Peregrin Source (BRPF1_HUMAN) Sequence A:  EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYL DHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLK YNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM Description Functional site 1) chain A residue 652 type sequence I description binding site for residue 9LT A 801 source : AC1 2) chain A residue 653 type sequence F description binding site for residue 9LT A 801 source : AC1 3) chain A residue 658 type sequence P description binding site for residue 9LT A 801 source : AC1 4) chain A residue 661 type sequence E description binding site for residue 9LT A 801 source : AC1 5) chain A residue 707 type sequence Y description binding site for residue 9LT A 801 source : AC1 6) chain A residue 708 type sequence N description binding site for residue 9LT A 801 source : AC1 7) chain A residue 714 type sequence F description binding site for residue 9LT A 801 source : AC1 8) chain A residue 734 type sequence R description binding site for residue 9LT A 801 source : AC1 9) chain A residue 738 type sequence K description binding site for residue 9LT A 801 source : AC1 10) chain A residue 702 type sequence S description binding site for residue NO3 A 802 source : AC2 11) chain A residue 705 type sequence L description binding site for residue NO3 A 802 source : AC2 12) chain A residue 706 type sequence K description binding site for residue NO3 A 802 source : AC2 13) chain A residue 715 type sequence Y description binding site for residue NO3 A 802 source : AC2 14) chain A residue 722 type sequence R description binding site for residue NO3 A 802 source : AC2 15) chain A residue 627 type sequence E description binding site for residue NO3 A 803 source : AC3 16) chain A residue 714 type sequence F description binding site for residue NO3 A 803 source : AC3 17) chain A residue 734 type sequence R description binding site for residue NO3 A 803 source : AC3 18) chain A residue 650-707 type prosite sequence GNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLN FDDFEEDFNLIVSNCLKY description BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY source prosite : PS00633

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