eF-site ID 5o1v-B PDB Code 5o1v Chain B click to enlarge Title Crystal structure of WNK3 kinase domain in a monophosphorylated apo state (A-loop swapped) Classification STRUCTURAL GENOMICS Compound Serine/threonine-protein kinase WNK3 Source (WNK3_HUMAN) Sequence B:  EMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEV AWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSW ESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSW CRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIG DLGLATLMRTXGTPEFMAPEMYEEHYDESVDVYAFGMCML EMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVK EIIEGCIRQNKSERLSIRDLLNHAFFAEDTG Description (1)  FAM83B Functional site 1) chain B residue 137 type sequence A description binding site for residue EDO B 501 source : AD2 2) chain B residue 139 type sequence A description binding site for residue EDO B 501 source : AD2 3) chain B residue 140 type sequence T description binding site for residue EDO B 501 source : AD2 4) chain B residue 207 type sequence V description binding site for residue EDO B 502 source : AD3 5) chain B residue 227 type sequence T description binding site for residue EDO B 502 source : AD3 6) chain B residue 228 type sequence E description binding site for residue EDO B 502 source : AD3 7) chain B residue 229 type sequence L description binding site for residue EDO B 502 source : AD3 8) chain B residue 230 type sequence M description binding site for residue EDO B 502 source : AD3 9) chain B residue 251 type sequence R description binding site for residue EDO B 503 source : AD4 10) chain B residue 403 type sequence A description binding site for residue EDO B 503 source : AD4 11) chain B residue 404 type sequence F description binding site for residue EDO B 503 source : AD4 12) chain B residue 323 type sequence E description binding site for residue EDO B 504 source : AD5 13) chain B residue 324 type sequence H description binding site for residue EDO B 504 source : AD5 14) chain B residue 325 type sequence Y description binding site for residue EDO B 504 source : AD5 15) chain B residue 159 type sequence K description binding site for residue EDO B 505 source : AD6 16) chain B residue 293 type sequence G description binding site for residue EDO B 505 source : AD6 17) chain B residue 294 type sequence D description binding site for residue EDO B 505 source : AD6 18) chain B residue 172 type sequence E description binding site for residue EDO B 506 source : AD7 19) chain B residue 294 type ACT_SITE sequence D description Proton acceptor => ECO:0000250|UniProtKB:Q9JIH7 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 227 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:Q9H4A3 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 277 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:Q9H4A3 source Swiss-Prot : SWS_FT_FI2 22) chain B residue 304 type MOD_RES sequence X description Phosphoserine; by autocatalysis => ECO:0000250|UniProtKB:Q9JIH7 source Swiss-Prot : SWS_FT_FI3

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