eF-site ID 5nvz-L PDB Code 5nvz Chain L click to enlarge Title pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-(1-acetylcyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 16) Classification LIGASE Compound Elongin-B Source Homo sapiens (Human) (VHL_HUMAN) Sequence L:  VLRSVNSREPSQVIFXNRSPRVVLPVWLNFDGEPQPYPTL PPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLN VDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIV RSLYEDLEDHPNVQKDLERLTQE Description Functional site 1) chain L residue 182 type sequence R description binding site for residue 9BN C 301 source : AC1 2) chain L residue 67 type sequence N description binding site for residue 9BN L 301 source : AC4 3) chain L residue 88 type sequence W description binding site for residue 9BN L 301 source : AC4 4) chain L residue 98 type sequence Y description binding site for residue 9BN L 301 source : AC4 5) chain L residue 99 type sequence P description binding site for residue 9BN L 301 source : AC4 6) chain L residue 107 type sequence R description binding site for residue 9BN L 301 source : AC4 7) chain L residue 109 type sequence I description binding site for residue 9BN L 301 source : AC4 8) chain L residue 110 type sequence H description binding site for residue 9BN L 301 source : AC4 9) chain L residue 111 type sequence S description binding site for residue 9BN L 301 source : AC4 10) chain L residue 112 type sequence Y description binding site for residue 9BN L 301 source : AC4 11) chain L residue 115 type sequence H description binding site for residue 9BN L 301 source : AC4 12) chain L residue 117 type sequence W description binding site for residue 9BN L 301 source : AC4

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