eF-site ID 5nvz-I PDB Code 5nvz Chain I click to enlarge Title pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-(1-acetylcyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 16) Classification LIGASE Compound Elongin-B Source Homo sapiens (Human) (VHL_HUMAN) Sequence I:  VLRSVNSREPSQVIFXNRSPRVVLPVWLNFDGEPQPYPTL PPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLN VDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIV RSLYEDLEDHPNVQKDLERLTQE Description Functional site 1) chain I residue 182 type sequence R description binding site for residue 9BN F 301 source : AC2 2) chain I residue 67 type sequence N description binding site for residue 9BN I 301 source : AC3 3) chain I residue 88 type sequence W description binding site for residue 9BN I 301 source : AC3 4) chain I residue 91 type sequence F description binding site for residue 9BN I 301 source : AC3 5) chain I residue 98 type sequence Y description binding site for residue 9BN I 301 source : AC3 6) chain I residue 99 type sequence P description binding site for residue 9BN I 301 source : AC3 7) chain I residue 107 type sequence R description binding site for residue 9BN I 301 source : AC3 8) chain I residue 109 type sequence I description binding site for residue 9BN I 301 source : AC3 9) chain I residue 110 type sequence H description binding site for residue 9BN I 301 source : AC3 10) chain I residue 111 type sequence S description binding site for residue 9BN I 301 source : AC3 11) chain I residue 112 type sequence Y description binding site for residue 9BN I 301 source : AC3 12) chain I residue 115 type sequence H description binding site for residue 9BN I 301 source : AC3 13) chain I residue 117 type sequence W description binding site for residue 9BN I 301 source : AC3

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