eF-site ID 5nvz-C PDB Code 5nvz Chain C click to enlarge Title pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-(1-acetylcyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 16) Classification LIGASE Compound Elongin-B Source Homo sapiens (Human) (VHL_HUMAN) Sequence C:  VLRSVNSREPSQVIFXNRSPRVVLPVWLNFDGEPQPYPTL PPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLN VDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIV RSLYEDLEDHPNVQKDLERLTQ Description Functional site 1) chain C residue 88 type sequence W description binding site for residue 9BN C 301 source : AC1 2) chain C residue 98 type sequence Y description binding site for residue 9BN C 301 source : AC1 3) chain C residue 99 type sequence P description binding site for residue 9BN C 301 source : AC1 4) chain C residue 109 type sequence I description binding site for residue 9BN C 301 source : AC1 5) chain C residue 110 type sequence H description binding site for residue 9BN C 301 source : AC1 6) chain C residue 111 type sequence S description binding site for residue 9BN C 301 source : AC1 7) chain C residue 112 type sequence Y description binding site for residue 9BN C 301 source : AC1 8) chain C residue 115 type sequence H description binding site for residue 9BN C 301 source : AC1 9) chain C residue 117 type sequence W description binding site for residue 9BN C 301 source : AC1 10) chain C residue 182 type sequence R description binding site for residue 9BN L 301 source : AC4

Display surface Download Links