|
|
eF-site ID
|
5nvz-A |
|
PDB Code
|
5nvz |
|
Chain
|
A |
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click to enlarge
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Title
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pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-(1-acetylcyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 16) |
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Classification
|
LIGASE |
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Compound
|
Elongin-B |
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Source
|
Homo sapiens (Human) (VHL_HUMAN) |
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Sequence
|
A: |
MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPD
EQRLYKDDQLLDDGKTLGEXGFTSQTARPQAPATVGLAFR
ADDTFEALXIEPFSSPPELPDVMK
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
1 |
| type |
MOD_RES |
| sequence |
M
|
| description |
N-acetylmethionine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
A |
| residue |
84 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0000250|UniProtKB:P62869
|
| source |
Swiss-Prot : SWS_FT_FI2
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