eF-site ID 5nt1-ABIJ PDB Code 5nt1 Chain A, B, I, J click to enlarge Title Complex of influenza A NS1 effector domain with TRIM25 coiled coil Classification LIGASE Compound E3 ubiquitin/ISG15 ligase TRIM25 Source Homo sapiens (Human) (NS1_I34A1) Sequence A:  SLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQD VRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKR VNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLE KASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELK QCIGRLQELTPSS B:  ASRYLTDMTLEEMSREWSMLIPKQKVAGPLCIRMDQAIMD KNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPS LPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRS I:  SLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQD VRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKR VNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLE KASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELK QCIGRLQELTPSS J:  ASRYLTDMTLEEMSREWSMLIPKQKVAGPLCIRMDQAIMD KNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPS LPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWR Description Functional site 1) chain B residue 108 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 110 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 126 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 4) chain J residue 108 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 5) chain J residue 110 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 6) chain J residue 126 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band II form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 278 type CROSSLNK sequence Y description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15); in band I form; by host => ECO:0000269|PubMed:20385878 source Swiss-Prot : SWS_FT_FI2

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