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eF-site ID
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5nnc-AB |
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PDB Code
|
5nnc |
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Chain
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A, B |
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click to enlarge
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Title
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Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac) |
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Classification
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TRANSCRIPTION |
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Compound
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Bromodomain-containing protein 4 |
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Source
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(Q5TEC6_HUMAN) |
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Sequence
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A: |
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAW
PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN
AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI
NELPT
|
| B: |
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAW
PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN
AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI
NELPT
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
80-139 |
| type |
prosite |
| sequence |
AWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYY
WNAQECIQDFNTMFTNCYIY
|
| description |
BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY
|
| source |
prosite : PS00633
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2)
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chain |
B |
| residue |
99 |
| type |
MOD_RES |
| sequence |
K
|
| description |
5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
|
| source |
Swiss-Prot : SWS_FT_FI2
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