eF-site ID 5nmk-A
PDB Code 5nmk
Chain A

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Title HLA A02 presenting SLFNTIAVL
Classification IMMUNE SYSTEM
Compound HLA class I histocompatibility antigen, A-2 alpha chain
Source Human immunodeficiency virus 1 (W0GUW4_9HIV1)
Sequence A:  GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA
ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT
LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG
KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL
EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT
FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
Description (1)  HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Gag protein


Functional site

1) chain A
residue 183
type
ligand
sequence D
description binding site for residue EDO A 301
source : AC1

2) chain A
residue 186
type
ligand
sequence K
description binding site for residue EDO A 301
source : AC1

3) chain A
residue 207
type
ligand
sequence S
description binding site for residue EDO A 301
source : AC1

4) chain A
residue 240
type
ligand
sequence T
description binding site for residue EDO A 301
source : AC1

5) chain A
residue 104
type
ligand
sequence G
description binding site for residue EDO A 302
source : AC2

6) chain A
residue 106
type
ligand
sequence D
description binding site for residue EDO A 302
source : AC2

7) chain A
residue 108
type
ligand
sequence R
description binding site for residue EDO A 302
source : AC2

8) chain A
residue 109
type
ligand
sequence F
description binding site for residue EDO A 302
source : AC2

9) chain A
residue 115
type
ligand
sequence Q
description binding site for residue EDO A 303
source : AC3

10) chain A
residue 19
type
ligand
sequence E
description binding site for residue EDO A 304
source : AC4

11) chain A
residue 20
type
ligand
sequence P
description binding site for residue EDO A 304
source : AC4

12) chain A
residue 71
type
ligand
sequence S
description binding site for residue EDO A 304
source : AC4

13) chain A
residue 72
type
ligand
sequence Q
description binding site for residue EDO A 304
source : AC4

14) chain A
residue 75
type
ligand
sequence R
description binding site for residue EDO A 304
source : AC4

15) chain A
residue 134
type
ligand
sequence T
description binding site for residue EDO A 305
source : AC5

16) chain A
residue 135
type
ligand
sequence A
description binding site for residue EDO A 305
source : AC5

17) chain A
residue 141
type
ligand
sequence Q
description binding site for residue EDO A 305
source : AC5

18) chain A
residue 144
type
ligand
sequence K
description binding site for residue EDO A 305
source : AC5

19) chain A
residue 44
type
ligand
sequence R
description binding site for residue EDO A 306
source : AC6

20) chain A
residue 45
type
ligand
sequence M
description binding site for residue EDO A 306
source : AC6

21) chain A
residue 60
type
ligand
sequence W
description binding site for residue EDO A 306
source : AC6

22) chain A
residue 104
type
ligand
sequence G
description binding site for residue GOL A 307
source : AC7

23) chain A
residue 105
type
ligand
sequence S
description binding site for residue GOL A 307
source : AC7

24) chain A
residue 106
type
ligand
sequence D
description binding site for residue GOL A 307
source : AC7

25) chain A
residue 48
type
ligand
sequence R
description binding site for residue SO4 A 308
source : AC8

26) chain A
residue 49
type
ligand
sequence A
description binding site for residue SO4 A 308
source : AC8

27) chain A
residue 50
type
ligand
sequence P
description binding site for residue SO4 A 308
source : AC8

28) chain A
residue 53
type
ligand
sequence E
description binding site for residue SO4 A 308
source : AC8

29) chain A
residue 220
type
ligand
sequence D
description binding site for residue SO4 A 309
source : AC9

30) chain A
residue 255
type
ligand
sequence Q
description binding site for residue SO4 A 309
source : AC9

31) chain A
residue 256
type
ligand
sequence R
description binding site for residue SO4 A 309
source : AC9

32) chain A
residue 273
type
ligand
sequence R
description binding site for residue SO4 A 309
source : AC9

33) chain A
residue 204
type
ligand
sequence W
description binding site for residue EDO B 301
source : AD1

34) chain A
residue 206
type
ligand
sequence L
description binding site for residue EDO B 301
source : AD1

35) chain A
residue 234
type
ligand
sequence R
description binding site for residue EDO B 301
source : AD1

36) chain A
residue 242
type
ligand
sequence Q
description binding site for residue EDO B 301
source : AD1

37) chain A
residue 238
type
ligand
sequence D
description binding site for residue EDO B 302
source : AD2

38) chain A
residue 97
type
ligand
sequence R
description binding site for residue EDO C 101
source : AD3

39) chain A
residue 147
type
ligand
sequence W
description binding site for residue EDO C 101
source : AD3

40) chain A
residue 2
type binding
ligand GOL: GLYCEROL
sequence S
description GLYCEROL binding site
source pdb_hetatom : GOL_5nmk_A_307

41) chain A
residue 104-106
type binding
ligand GOL: GLYCEROL
sequence GSD
description GLYCEROL binding site
source pdb_hetatom : GOL_5nmk_A_307

42) chain A
residue 110
type binding
ligand GOL: GLYCEROL
sequence L
description GLYCEROL binding site
source pdb_hetatom : GOL_5nmk_A_307

43) chain A
residue 8
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence F
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_303

44) chain A
residue 98
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence M
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_303

45) chain A
residue 115
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence Q
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_303

46) chain A
residue 11
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence S
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_304

47) chain A
residue 19-22
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence EPRF
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_304

48) chain A
residue 38
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence S
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_304

49) chain A
residue 71-72
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence SQ
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_304

50) chain A
residue 75
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence R
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_304

51) chain A
residue 44-47
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence RMEP
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_306

52) chain A
residue 60
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence W
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_306

53) chain A
residue 64
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence T
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_306

54) chain A
residue 97
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence R
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

55) chain A
residue 114
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence H
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

56) chain A
residue 133
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence W
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

57) chain A
residue 147
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence W
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

58) chain A
residue 152
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence V
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

59) chain A
residue 156
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence L
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_C_101

60) chain A
residue 103-106
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence VGSD
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_302

61) chain A
residue 108-110
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence RFL
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_302

62) chain A
residue 133-135
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence WTA
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_305

63) chain A
residue 141
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence Q
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_305

64) chain A
residue 144
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence K
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_305

65) chain A
residue 181
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence R
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

66) chain A
residue 183
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence D
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

67) chain A
residue 186
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence K
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

68) chain A
residue 207
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence S
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

69) chain A
residue 238
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence D
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

70) chain A
residue 240
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence T
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_A_301

71) chain A
residue 204
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence W
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_B_301

72) chain A
residue 206
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence L
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_B_301

73) chain A
residue 234
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence R
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_B_301

74) chain A
residue 242
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence Q
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_B_301

75) chain A
residue 238
type binding
ligand EDO: 1,2-ETHANEDIOL
sequence D
description 1,2-ETHANEDIOL binding site
source pdb_hetatom : EDO_5nmk_B_302


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