eF-site/Summary 5nme-F

eF-site ID	5nme-F
PDB Code	5nme
Chain	F

click to enlarge

Title	868 TCR in complex with HLA A02 presenting SLYNTVATL
Classification	IMMUNE SYSTEM
Compound	HLA class I histocompatibility antigen, A-2 alpha chain
Source	Homo sapiens (Human) (5NME)

Sequence	F:	GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP

Description

Functional site


1)	chain	F
	residue	192
	type
	sequence	H
	description	binding site for residue GOL F 301
	source	: AC7

2)	chain	F
	residue	193
	type
	sequence	A
	description	binding site for residue GOL F 301
	source	: AC7

3)	chain	F
	residue	86
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:19159218
	source	Swiss-Prot : SWS_FT_FI4

4)	chain	F
	residue	7
	type	MOD_RES
	sequence	Y
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

5)	chain	F
	residue	73
	type	MOD_RES
	sequence	T
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

6)	chain	F
	residue	84
	type	MOD_RES
	sequence	Y
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

7)	chain	F
	residue	143
	type	MOD_RES
	sequence	T
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

8)	chain	F
	residue	146
	type	MOD_RES
	sequence	K
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

9)	chain	F
	residue	171
	type	MOD_RES
	sequence	Y
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

10)	chain	F
	residue	116
	type	CARBOHYD
	sequence	Y
	description	N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI2

11)	chain	F
	residue	159
	type	CARBOHYD
	sequence	Y
	description	N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI2