eF-site ID 5n9x-AB PDB Code 5n9x Chain A, B click to enlarge Title Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, ligand bound structure Classification LIGASE Compound Adenylation domain Source Streptomyces sp (H6SG27_STRSQ) Sequence A:  GATLVDLFSRAAMEMPDRTALHIDDEKISYGLLHSWAEGL ADLLHDAGVRKGDRVALRMPPGANAIAAMLGILRAGAAYV PLDIRNPPARNAFIVTDSQVVALVGDPIPEYTGPLVTEEN VAALRPGPERPGPQDVAYIIYTSGTTGRPKGVPVRHGNVT ALFEACSRLFSFSADDRWLLFHSMAFDFSVWEIWGALSTG AELVVLPYWTARTPVETARVVRDRGITVLNQTPTAFGALT TAVLGEGIDLPELRYVVFGGEKLTPAVVRPWAKRFGLDRP HLINMYGITETTVHATFHRLTEDDLAAEDSVIGRPLPGFT HRIVTEDGRDAATGEPGELWLAGPQVSEGYLNRPELTAER FTTGPPPRYYHSGDLVSRRAGGDLVYQGRADLQVKLRGHR IELSDVEAAVRTHPAVVDAVVWVHEFAPGDSRLVCAYTAP DARALRAHVKTVLPSYMQPSQYLALPELPRTINGKADRAS VARAFDERR B:  FGATLVDLFSRAAMEMPDRTALHIDDEKISYGLLHSWAEG LADLLHDAGVRKGDRVALRMPPGANAIAAMLGILRAGAAY VPLDIRNPPARNAFIVTDSQVVALVGDPTGPLVTEENVAA LRDREGPERPGPQDVAYIIYTSGTTGRPKGVPVRHGNVTA LFEACSRLFSFSADDRWLLFHSMAFDFSVWEIWGALSTGA ELVVLPTARTPVETARVVRDRGITVLNQTPTAFGALTTAV LGEGIDLPELRYVVFGGEKLTPAVVRPWAKRFGLDRPHLI NMYGITETTVHATFHRLTEDDLAAEDSVIGRPLPGFTHRI VTEDGRDAATGEPGELWLAGPQVSEGYLNRPELTAERFTT GPPRYYHSGDLVSRRAGGDLVYQGRADLQVKLRGHRIELS DVEAAVRTHPAVVDAVVWVHEFAPGDSRLVCAYTAQADAR ALRAHVKTVLPSYMQPSQYLALPELPRTINGKADRASVAR AFDERR Description Functional site 1) chain A residue 211 type sequence F description binding site for residue THR A 601 source : AC1 2) chain A residue 212 type sequence D description binding site for residue THR A 601 source : AC1 3) chain A residue 213 type sequence F description binding site for residue THR A 601 source : AC1 4) chain A residue 285 type sequence G description binding site for residue THR A 601 source : AC1 5) chain A residue 312 type sequence G description binding site for residue THR A 601 source : AC1 6) chain A residue 313 type sequence I description binding site for residue THR A 601 source : AC1 7) chain A residue 318 type sequence V description binding site for residue THR A 601 source : AC1 8) chain A residue 515 type sequence K description binding site for residue THR A 601 source : AC1 9) chain A residue 167 type sequence T description binding site for residue ATP A 602 source : AC2 10) chain A residue 168 type sequence S description binding site for residue ATP A 602 source : AC2 11) chain A residue 175 type sequence K description binding site for residue ATP A 602 source : AC2 12) chain A residue 285 type sequence G description binding site for residue ATP A 602 source : AC2 13) chain A residue 286 type sequence E description binding site for residue ATP A 602 source : AC2 14) chain A residue 287 type sequence K description binding site for residue ATP A 602 source : AC2 15) chain A residue 309 type sequence N description binding site for residue ATP A 602 source : AC2 16) chain A residue 310 type sequence M description binding site for residue ATP A 602 source : AC2 17) chain A residue 311 type sequence Y description binding site for residue ATP A 602 source : AC2 18) chain A residue 312 type sequence G description binding site for residue ATP A 602 source : AC2 19) chain A residue 313 type sequence I description binding site for residue ATP A 602 source : AC2 20) chain A residue 314 type sequence T description binding site for residue ATP A 602 source : AC2 21) chain A residue 315 type sequence E description binding site for residue ATP A 602 source : AC2 22) chain A residue 406 type sequence D description binding site for residue ATP A 602 source : AC2 23) chain A residue 418 type sequence Y description binding site for residue ATP A 602 source : AC2 24) chain A residue 421 type sequence R description binding site for residue ATP A 602 source : AC2 25) chain A residue 515 type sequence K description binding site for residue ATP A 602 source : AC2 26) chain A residue 421 type sequence R description binding site for residue MG A 603 source : AC3 27) chain B residue 167 type sequence T description binding site for residue 8QN B 601 source : AC4 28) chain B residue 212 type sequence D description binding site for residue 8QN B 601 source : AC4 29) chain B residue 213 type sequence F description binding site for residue 8QN B 601 source : AC4 30) chain B residue 285 type sequence G description binding site for residue 8QN B 601 source : AC4 31) chain B residue 286 type sequence E description binding site for residue 8QN B 601 source : AC4 32) chain B residue 287 type sequence K description binding site for residue 8QN B 601 source : AC4 33) chain B residue 309 type sequence N description binding site for residue 8QN B 601 source : AC4 34) chain B residue 310 type sequence M description binding site for residue 8QN B 601 source : AC4 35) chain B residue 311 type sequence Y description binding site for residue 8QN B 601 source : AC4 36) chain B residue 312 type sequence G description binding site for residue 8QN B 601 source : AC4 37) chain B residue 313 type sequence I description binding site for residue 8QN B 601 source : AC4 38) chain B residue 314 type sequence T description binding site for residue 8QN B 601 source : AC4 39) chain B residue 318 type sequence V description binding site for residue 8QN B 601 source : AC4 40) chain B residue 406 type sequence D description binding site for residue 8QN B 601 source : AC4 41) chain B residue 418 type sequence Y description binding site for residue 8QN B 601 source : AC4 42) chain B residue 421 type sequence R description binding site for residue 8QN B 601 source : AC4 43) chain B residue 513 type sequence N description binding site for residue 8QN B 601 source : AC4 44) chain B residue 515 type sequence K description binding site for residue 8QN B 601 source : AC4 45) chain A residue 164-175 type prosite sequence IIYTSGTTGRPK description AMP_BINDING Putative AMP-binding domain signature. IIYTSGTTGrPK source prosite : PS00455

Display surface Download Links