eF-site ID 5n9w-B PDB Code 5n9w Chain B click to enlarge Title Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, apo structure Classification TRANSFERASE Compound Adenylation domain Source Streptomyces sp (H6SG27_STRSQ) Sequence B:  EFGATLVDLFSRAAMEMPDRTALHIKISYGLLHSWAEGLA DLLHDAGVRKGDRVALRMPPGANAIAAMLGILRAGAAYVP LDIRNPPARNAFIVTDSQVVALVGDPGGPLVTEENVAALR PERPGPQDVAYIIYTSGTTGRPKGVPVRHGNVTALFEACS RLFSFSADDRWLLFHSMAFDFSVWEIWGALSTGAELVVLP TPVETARVVRDRGITVLNQTPTAFGALTTAVLGEGIDLPE LRYVVFGGEKLTPAVVRPWAKRFGLDRPHLINMYGITETT VHATFHRLTEDDLAAEDSVIGRPLPGFTHRIVTEDGRDAA TGEPGELWLAGPQVSEGYLNRPELTAERFTTGPRYYHSGD LVSRRAGGDLVYQGRADLQVKLRGHRIELSDVEAAVRTHP AVVDAVVWVHEFAPGDSRLVCAYTAQGPDARALRAHVKTV LPSYMQPSQYLALPELPRTINGKADRASVARAFDERR Description Functional site 1) chain B residue 212 type sequence D description binding site for residue ACT B 601 source : AC2 2) chain B residue 285 type sequence G description binding site for residue ACT B 601 source : AC2 3) chain B residue 312 type sequence G description binding site for residue ACT B 601 source : AC2 4) chain B residue 318 type sequence V description binding site for residue ACT B 601 source : AC2 5) chain B residue 262 type sequence G description binding site for residue ACT B 602 source : AC3 6) chain B residue 263 type sequence A description binding site for residue ACT B 602 source : AC3 7) chain B residue 266 type sequence T description binding site for residue ACT B 602 source : AC3 8) chain B residue 443 type sequence R description binding site for residue ACT B 602 source : AC3 9) chain B residue 445 type sequence H description binding site for residue ACT B 602 source : AC3 10) chain B residue 448 type sequence V description binding site for residue ACT B 602 source : AC3 11) chain B residue 472 type sequence Q description binding site for residue ACT B 602 source : AC3

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