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eF-site ID
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5n9w-A |
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PDB Code
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5n9w |
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Chain
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A |
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click to enlarge
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Title
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Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, apo structure |
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Classification
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TRANSFERASE |
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Compound
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Adenylation domain |
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Source
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Streptomyces sp (H6SG27_STRSQ) |
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Sequence
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A: |
ATLVDLFSRAAMEMPDRTALHIDDEKISYGLLHSWAEGLA
DLLHDAGVRKGDRVALRMPPGANAIAAMLGILRAGAAYVP
LDIRNPPARNAFIVTDSQVVALVGDPGYTGPLVTEENVAA
LRDRGPERPGPQDVAYIIYTSGRPKGVPVRHGNVTALFEA
CSRLFSFSADDRWLLFHSMAFDFSVWEIWGALSTGAELVV
LTPVETARVVRDRGITVLNQTPTAFGALTTAVLGEGIDLP
ELRYVVFGGEKLTPAVVRPWAKRFGLDRPHLINMYGITET
TVHATFHRLTEDDLAAEDSVIGRPLPGFTHRIVTEDGRDA
ATGEPGELWLAGPQVSEGYLNRPELTAERFTTPPRYYHSG
DLVSRRAGGDLVYQGRADLQVKLRGHRIELSDVEAAVRTH
PAVVDAVVWVHEFAPGDSRLVCAYTAQPDARALRAHVKTV
LPSYMQPSQYLALPELPRTINGKADRASVARAFDERR
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Description
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Functional site
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1)
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chain |
A |
| residue |
279 |
| type |
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| sequence |
R
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| description |
binding site for residue ACT A 601
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| source |
: AC1
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2)
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chain |
A |
| residue |
164-175 |
| type |
prosite |
| sequence |
IIYTSGRPK
|
| description |
AMP_BINDING Putative AMP-binding domain signature. IIYTSGTTGrPK
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| source |
prosite : PS00455
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