eF-site ID 5n7w-ABHLXY PDB Code 5n7w Chain A, B, H, L, X, Y click to enlarge Title Computationally designed functional antibody Classification IMMUNE SYSTEM Compound Antibody Fragment Heavy Chain Source (IL17_HUMAN) Sequence A:  QVKLVQSGAEVKKPGASVKVSCKASGYTFSSYWIAWVRQA PGQGLEWIGEILPGSGSTNYAQKFQGRATMTADTSTSTVY MELSSLRSEDTAVYYCARFPYYYGNWDVWGQGTTVTVSSA STKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTY ICNVNHKPSNTKVDKRVEPK B:  DIQMTQSPSSLSASVGDRVTITCQASQDIWWYLNWYQQKP GKAPKLLIYYTSRLHSGVPSRFSGSGSGTDYTFTISSLQP EDIATYYCQQGFYLPWTFGGGTKVEIKLGQPKAAPSVTLF PPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG VETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHE GSTVEKTVAP H:  QVKLVQSGAEVKKPGASVKVSCKASGYTFSSYWIAWVRQA PGQGLEWIGEILPGSGSTNYAQKFQGRATMTADTSTSTVY MELSSLRSEDTAVYYCARFPYYYGNWDVWGQGTTVTVSSA STKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALT SGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNH KPSNTKVDKRVEPKSC L:  DIQMTQSPSSLSASVGDRVTITCQASQDIWWYLNWYQQKP GKAPKLLIYYTSRLHSGVPSRFSGSGSGTDYTFTISSLQP EDIATYYCQQGFYLPWTFGGGTKVEIKLGQPKAAPSVTLF PPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG VETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHE GSTVEKTVAPT X:  NPGCPNSEDKNFPRTVMVNLNISDYYNRSTSPWNLHRNED PERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILV LRREPPHCPNSFRLEKILVSVGCTCVTP Y:  CPNSEDKNFPRTVMVNLNIHDYYNRSTSPWNLHRNEDPER YPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRR EPPHCPNSFRLEKILVSVGCTCVTP Description (1)  Antibody Fragment Heavy Chain, Antibody Fragment Light Chain, Interleukin-17A Functional site 1) chain A residue 200-206 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 2) chain B residue 193-199 type prosite sequence YSCQVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 3) chain X residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 4) chain Y residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1

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