eF-site ID 5n6l-B PDB Code 5n6l Chain B click to enlarge Title Structure of the membrane integral lipoprotein N-acyltransferase Lnt C387A mutant from E. coli Classification TRANSFERASE Compound Apolipoprotein N-acyltransferase Source (LNT_ECOLI) Sequence B:  FASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLM GLQALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATF GGMPGPVNIFLVVLLAAYLSLYTGLFAGVLSRLWPKTTWL RVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPLKG LAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLF ALPFPLRYIQWFTPQPEKTIQVSMVQGDIPQSLKWDEGQL LNTLKIYYNATAPLMGKSSLIIWPESAITDLEINQQPFLK ALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKG APYSYESADRYNKNHLVPFGEFVPLESFSRGPYIQPPLSA NGIELTAAIAYEIILGEQVRDNFRPDTDYLLTISNDAWFG KSIGPWQHFQMARMRALELARPLLRSTNNGITAVIGPQGE IQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTAL FGFAAVLMSLR Description Functional site 1) chain B residue 211 type sequence I description binding site for residue OLC A 619 source : AE1 2) chain B residue 212 type sequence Q description binding site for residue OLC A 619 source : AE1 3) chain B residue 22 type sequence A description binding site for residue OLC B 601 source : AF1 4) chain B residue 26 type sequence L description binding site for residue OLC B 601 source : AF1 5) chain B residue 31 type sequence Y description binding site for residue OLC B 601 source : AF1 6) chain B residue 70 type sequence S description binding site for residue OLC B 601 source : AF1 7) chain B residue 73 type sequence N description binding site for residue OLC B 601 source : AF1 8) chain B residue 178 type sequence M description binding site for residue OLC B 602 source : AF2 9) chain B residue 494 type sequence L description binding site for residue OLC B 602 source : AF2 10) chain B residue 498 type sequence F description binding site for residue OLC B 602 source : AF2 11) chain B residue 7 type sequence I description binding site for residue OLC B 603 source : AF3 12) chain B residue 13 type sequence R description binding site for residue OLC B 603 source : AF3 13) chain B residue 46 type sequence A description binding site for residue OLC B 603 source : AF3 14) chain B residue 47 type sequence L description binding site for residue OLC B 603 source : AF3 15) chain B residue 49 type sequence F description binding site for residue OLC B 603 source : AF3 16) chain B residue 134 type sequence V description binding site for residue OLC B 604 source : AF4 17) chain B residue 394 type sequence E description binding site for residue OLC B 604 source : AF4 18) chain B residue 488 type sequence N description binding site for residue OLC B 604 source : AF4 19) chain B residue 489 type sequence W description binding site for residue OLC B 604 source : AF4 20) chain B residue 492 type sequence W description binding site for residue OLC B 604 source : AF4 21) chain B residue 499 type sequence G description binding site for residue OLC B 604 source : AF4 22) chain B residue 54 type sequence L description binding site for residue OLC B 605 source : AF5 23) chain B residue 96 type sequence L description binding site for residue OLC B 605 source : AF5 24) chain B residue 103 type sequence L description binding site for residue OLC B 605 source : AF5 25) chain B residue 210 type sequence Y description binding site for residue OLC B 606 source : AF6 26) chain B residue 211 type sequence I description binding site for residue OLC B 606 source : AF6 27) chain B residue 212 type sequence Q description binding site for residue OLC B 606 source : AF6 28) chain B residue 209 type sequence R description binding site for residue OLC B 607 source : AF7 29) chain B residue 137 type sequence F description binding site for residue OLC B 608 source : AF8 30) chain B residue 141 type sequence W description binding site for residue OLC B 608 source : AF8 31) chain B residue 488 type sequence N description binding site for residue OLC B 608 source : AF8 32) chain B residue 492 type sequence W description binding site for residue OLC B 608 source : AF8 33) chain B residue 141 type sequence W description binding site for residue GOL B 609 source : AF9 34) chain B residue 143 type sequence L description binding site for residue GOL B 609 source : AF9 35) chain B residue 144 type sequence T description binding site for residue GOL B 609 source : AF9 36) chain B residue 277 type sequence Q description binding site for residue GOL B 610 source : AG1 37) chain B residue 280 type sequence F description binding site for residue GOL B 610 source : AG1 38) chain B residue 32 type sequence D description binding site for residue GOL B 611 source : AG2 39) chain B residue 244 type sequence N description binding site for residue GOL B 612 source : AG3 40) chain B residue 387 type ACT_SITE sequence A description Nucleophile => ECO:0000255|HAMAP-Rule:MF_01148, ECO:0000305|PubMed:28675161 source Swiss-Prot : SWS_FT_FI6 41) chain B residue 49-52 type TOPO_DOM sequence FNRR description Cytoplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI1 42) chain B residue 117-120 type TOPO_DOM sequence PKTT description Cytoplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI1 43) chain B residue 190-191 type TOPO_DOM sequence RN description Cytoplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI1 44) chain B residue 34-48 type TRANSMEM sequence WPAAIISLMGLQALT description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 45) chain B residue 53-68 type TRANSMEM sequence PLQSAAIGFCWGFGLF description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 46) chain B residue 87-116 type TRANSMEM sequence GPVNIFLVVLLAAYLSLYTGLFAGVLSRLW description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 47) chain B residue 121-141 type TRANSMEM sequence WLRVAIAAPALWQVTEFLRGW description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 48) chain B residue 169-189 type TRANSMEM sequence VEAINFLLMMVSGLLALALVK description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 49) chain B residue 192-210 type TRANSMEM sequence WRPLVVAVVLFALPFPLRY description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 50) chain B residue 488-508 type TRANSMEM sequence NWPLWVLTALFGFAAVLMSLR description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 51) chain B residue 10-27 type TRANSMEM sequence QRIRLLLALLFGACGTLA description Helical => ECO:0000269|PubMed:28675161 source Swiss-Prot : SWS_FT_FI2 52) chain B residue 28-33 type TOPO_DOM sequence FSPYDV description Periplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI3 53) chain B residue 69-86 type TOPO_DOM sequence GSGINWVYVSIATFGGMP description Periplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI3 54) chain B residue 142-168 type TOPO_DOM sequence VLTGFPWLQFGYSQIDGPLKGLAPIMG description Periplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI3 55) chain B residue 211-487 type TOPO_DOM sequence IQWFTPQPEKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYY NATAPLMGKSSLIIWPESAITDLEINQQPFLKALDGELRD KGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESA DRYNKNHLVPFGEFVPLESFSRGPYIQPPLSANGIELTAA IAYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQH FQMARMRALELARPLLRSTNNGITAVIGPQGEIQAMIPQF TREVLTTNVTPTTGLTPYARTG description Periplasmic => ECO:0000269|PubMed:28675161, ECO:0000269|PubMed:28885614 source Swiss-Prot : SWS_FT_FI3 56) chain B residue 267 type ACT_SITE sequence E description Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01148, ECO:0000305|PubMed:28675161 source Swiss-Prot : SWS_FT_FI4 57) chain B residue 335 type ACT_SITE sequence K description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01148, ECO:0000305|PubMed:28675161 source Swiss-Prot : SWS_FT_FI5

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