eF-site ID 5mwg-A PDB Code 5mwg Chain A click to enlarge Title Crystal structure of the human BRPF1 bromodomain in complex with BZ091 Classification DNA BINDING PROTEIN Compound Peregrin Source (BRPF1_HUMAN) Sequence A:  LTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHI KKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNA KDTIFYRAAVRLREQGGAVLRQARRQAEKM Description (1)  Peregrin Functional site 1) chain A residue 652 type sequence I description binding site for residue WGX A 801 source : AC1 2) chain A residue 653 type sequence F description binding site for residue WGX A 801 source : AC1 3) chain A residue 657 type sequence V description binding site for residue WGX A 801 source : AC1 4) chain A residue 658 type sequence P description binding site for residue WGX A 801 source : AC1 5) chain A residue 661 type sequence E description binding site for residue WGX A 801 source : AC1 6) chain A residue 662 type sequence V description binding site for residue WGX A 801 source : AC1 7) chain A residue 704 type sequence C description binding site for residue WGX A 801 source : AC1 8) chain A residue 707 type sequence Y description binding site for residue WGX A 801 source : AC1 9) chain A residue 708 type sequence N description binding site for residue WGX A 801 source : AC1 10) chain A residue 714 type sequence F description binding site for residue WGX A 801 source : AC1 11) chain A residue 630 type sequence L description binding site for residue NO3 A 802 source : AC2 12) chain A residue 631 type sequence T description binding site for residue NO3 A 802 source : AC2 13) chain A residue 634 type sequence L description binding site for residue NO3 A 802 source : AC2 14) chain A residue 635 type sequence I description binding site for residue NO3 A 802 source : AC2 15) chain A residue 638 type sequence R description binding site for residue NO3 A 802 source : AC2 16) chain A residue 639 type sequence K description binding site for residue WGX B 801 source : AC3 17) chain A residue 650-707 type prosite sequence GNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLN FDDFEEDFNLIVSNCLKY description BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY source prosite : PS00633

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