eF-site ID 5mur-E PDB Code 5mur Chain E click to enlarge Title X-ray structure of the F14'A mutant of GLIC in complex with propofol Classification TRANSPORT PROTEIN Compound Proton-gated ion channel Source (GLIC_GLOVI) Sequence E:  VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLS LSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENA RDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIES FTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILP MLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVET NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQ PARAASITRASRIAFPVVFLLANIILAFLFF Description Functional site 1) chain E residue 77 type sequence R description binding site for residue ACT D 405 source : AE3 2) chain E residue 131 type sequence I description binding site for residue ACT D 405 source : AE3 3) chain E residue 181 type sequence E description binding site for residue ACT D 405 source : AE3 4) chain E residue 42 type sequence F description binding site for residue ACT E 401 source : AE4 5) chain E residue 105 type sequence R description binding site for residue ACT E 401 source : AE4 6) chain E residue 74 type sequence P description binding site for residue ACT E 402 source : AE5 7) chain E residue 76 type sequence I description binding site for residue ACT E 402 source : AE5 8) chain E residue 85 type sequence R description binding site for residue ACT E 402 source : AE5 9) chain E residue 102 type sequence Y description binding site for residue ACT E 402 source : AE5 10) chain E residue 78 type sequence F description binding site for residue CL E 403 source : AE6 11) chain E residue 68 type sequence P description binding site for residue NA E 404 source : AE7 12) chain E residue 71 type sequence I description binding site for residue NA E 404 source : AE7 13) chain E residue 118 type sequence R description binding site for residue PLC E 405 source : AE8 14) chain E residue 121 type sequence F description binding site for residue PLC E 405 source : AE8 15) chain E residue 254 type sequence Y description binding site for residue PLC E 405 source : AE8 16) chain E residue 307 type sequence N description binding site for residue PLC E 405 source : AE8 17) chain E residue 315 type sequence F description binding site for residue PLC E 405 source : AE8 18) chain E residue 119 type sequence Y description binding site for residue PFL E 406 source : AE9 19) chain E residue 120 type sequence P description binding site for residue PFL E 406 source : AE9 20) chain E residue 197 type sequence Y description binding site for residue PFL E 406 source : AE9 21) chain E residue 201 type sequence I description binding site for residue PFL E 406 source : AE9 22) chain E residue 205 type sequence M description binding site for residue PFL E 406 source : AE9 23) chain E residue 255 type sequence T description binding site for residue PFL E 406 source : AE9 24) chain E residue 258 type sequence I description binding site for residue PFL E 406 source : AE9 25) chain E residue 259 type sequence I description binding site for residue PFL E 406 source : AE9 26) chain E residue 194-216 type TRANSMEM sequence YFSYIPNIILPMLFILFISWTAF description Helical source Swiss-Prot : SWS_FT_FI2 27) chain E residue 220-244 type TRANSMEM sequence SYEANVTLVVSTLIAHIAANILVET description Helical source Swiss-Prot : SWS_FT_FI2 28) chain E residue 253-281 type TRANSMEM sequence TYTGAIIFMIYLFYFVAVIEVTVQHYLKV description Helical source Swiss-Prot : SWS_FT_FI2 29) chain E residue 245-252 type TOPO_DOM sequence NLPKTPYM description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 30) chain E residue 282-284 type TOPO_DOM sequence ESQ description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 31) chain E residue 217-219 type TOPO_DOM sequence WST description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3

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