eF-site ID 5mur-D PDB Code 5mur Chain D click to enlarge Title X-ray structure of the F14'A mutant of GLIC in complex with propofol Classification TRANSPORT PROTEIN Compound Proton-gated ion channel Source (GLIC_GLOVI) Sequence D:  VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLS LSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENA RDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIES FTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILP MLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVET NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQ PARAASITRASRIAFPVVFLLANIILAFLFF Description Functional site 1) chain D residue 77 type sequence R description binding site for residue ACT C 405 source : AD7 2) chain D residue 131 type sequence I description binding site for residue ACT C 405 source : AD7 3) chain D residue 181 type sequence E description binding site for residue ACT C 405 source : AD7 4) chain D residue 74 type sequence P description binding site for residue ACT D 401 source : AD8 5) chain D residue 76 type sequence I description binding site for residue ACT D 401 source : AD8 6) chain D residue 85 type sequence R description binding site for residue ACT D 401 source : AD8 7) chain D residue 102 type sequence Y description binding site for residue ACT D 401 source : AD8 8) chain D residue 78 type sequence F description binding site for residue CL D 402 source : AD9 9) chain D residue 5 type sequence V description binding site for residue NA D 403 source : AE1 10) chain D residue 68 type sequence P description binding site for residue NA D 403 source : AE1 11) chain D residue 71 type sequence I description binding site for residue NA D 403 source : AE1 12) chain D residue 72 type sequence W description binding site for residue NA D 403 source : AE1 13) chain D residue 73 type sequence I description binding site for residue NA D 403 source : AE1 14) chain D residue 118 type sequence R description binding site for residue PLC D 404 source : AE2 15) chain D residue 121 type sequence F description binding site for residue PLC D 404 source : AE2 16) chain D residue 194 type sequence Y description binding site for residue PLC D 404 source : AE2 17) chain D residue 254 type sequence Y description binding site for residue PLC D 404 source : AE2 18) chain D residue 307 type sequence N description binding site for residue PLC D 404 source : AE2 19) chain D residue 42 type sequence F description binding site for residue ACT D 405 source : AE3 20) chain D residue 105 type sequence R description binding site for residue ACT D 405 source : AE3 21) chain D residue 194-216 type TRANSMEM sequence YFSYIPNIILPMLFILFISWTAF description Helical source Swiss-Prot : SWS_FT_FI2 22) chain D residue 220-244 type TRANSMEM sequence SYEANVTLVVSTLIAHIAANILVET description Helical source Swiss-Prot : SWS_FT_FI2 23) chain D residue 253-281 type TRANSMEM sequence TYTGAIIFMIYLFYFVAVIEVTVQHYLKV description Helical source Swiss-Prot : SWS_FT_FI2 24) chain D residue 245-252 type TOPO_DOM sequence NLPKTPYM description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 25) chain D residue 217-219 type TOPO_DOM sequence WST description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 26) chain D residue 282-284 type TOPO_DOM sequence ESQ description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links